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Clinical Cancer Research
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Cancer Therapy: Preclinical

Discordant In Vitro and In Vivo Chemopotentiating Effects of the PARP Inhibitor Veliparib in Temozolomide-Sensitive versus -Resistant Glioblastoma Multiforme Xenografts

Shiv K. Gupta, Ann C. Mladek, Brett L. Carlson, Felix Boakye-Agyeman, Katrina K. Bakken, Sani H. Kizilbash, Mark A. Schroeder, Joel Reid and Jann N. Sarkaria
Shiv K. Gupta
Departments of 1Radiation Oncology, and
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Ann C. Mladek
Departments of 1Radiation Oncology, and
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Brett L. Carlson
Departments of 1Radiation Oncology, and
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Felix Boakye-Agyeman
2Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester Minnesota
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Katrina K. Bakken
Departments of 1Radiation Oncology, and
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Sani H. Kizilbash
Departments of 1Radiation Oncology, and
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Mark A. Schroeder
Departments of 1Radiation Oncology, and
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Joel Reid
2Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester Minnesota
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Jann N. Sarkaria
Departments of 1Radiation Oncology, and
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  • For correspondence: sarkaria.jann@mayo.edu
DOI: 10.1158/1078-0432.CCR-13-3446 Published July 2014
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Total459531292123

Cited By

Article Information

Volume 20, Issue 14, pp. 3730-3741

DOI 
https://doi.org/10.1158/1078-0432.CCR-13-3446
PubMed 
24838527

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received December 20, 2013
  • Revision received May 6, 2014
  • Accepted May 8, 2014
  • Published first May 16, 2014.

Article Versions

  • Previous version (May 16, 2014 - 07:34).
  • Previous version (June 30, 2014 - 07:23).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2014 American Association for Cancer Research.

Author Information

  1. Shiv K. Gupta1,
  2. Ann C. Mladek1,
  3. Brett L. Carlson1,
  4. Felix Boakye-Agyeman2,
  5. Katrina K. Bakken1,
  6. Sani H. Kizilbash1,
  7. Mark A. Schroeder1,
  8. Joel Reid2, and
  9. Jann N. Sarkaria1,*
  1. Authors' Affiliations: Departments of 1Radiation Oncology, and
  2. 2Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester Minnesota
  1. ↵*Corresponding Author:
    Jann N. Sarkaria, Department of Radiation Oncology, Mayo Clinic, 200 First Street South West, Rochester, MN 55905. Phone: 507-284-8227/507-284-9025; Fax: 507-284-3906; E-mail: sarkaria.jann{at}mayo.edu
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Clinical Cancer Research: 20 (14)
July 2014
Volume 20, Issue 14
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Discordant In Vitro and In Vivo Chemopotentiating Effects of the PARP Inhibitor Veliparib in Temozolomide-Sensitive versus -Resistant Glioblastoma Multiforme Xenografts
Shiv K. Gupta, Ann C. Mladek, Brett L. Carlson, Felix Boakye-Agyeman, Katrina K. Bakken, Sani H. Kizilbash, Mark A. Schroeder, Joel Reid and Jann N. Sarkaria
Clin Cancer Res July 15 2014 (20) (14) 3730-3741; DOI: 10.1158/1078-0432.CCR-13-3446

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Discordant In Vitro and In Vivo Chemopotentiating Effects of the PARP Inhibitor Veliparib in Temozolomide-Sensitive versus -Resistant Glioblastoma Multiforme Xenografts
Shiv K. Gupta, Ann C. Mladek, Brett L. Carlson, Felix Boakye-Agyeman, Katrina K. Bakken, Sani H. Kizilbash, Mark A. Schroeder, Joel Reid and Jann N. Sarkaria
Clin Cancer Res July 15 2014 (20) (14) 3730-3741; DOI: 10.1158/1078-0432.CCR-13-3446
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