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Biology of Human Tumors

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma

Tomasz P. Radon, Nathalie J. Massat, Richard Jones, Wasfi Alrawashdeh, Laurent Dumartin, Darren Ennis, Stephen W. Duffy, Hemant M. Kocher, Stephen P. Pereira, Luisa Guarner (posthumous), Cristiane Murta-Nascimento, Francisco X. Real, Núria Malats, John Neoptolemos, Eithne Costello, William Greenhalf, Nick R. Lemoine and Tatjana Crnogorac-Jurcevic
Tomasz P. Radon
1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Nathalie J. Massat
2Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom.
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Richard Jones
3MS Bioworks, LLC, Ann Arbor, Michigan.
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Wasfi Alrawashdeh
1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Laurent Dumartin
1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Darren Ennis
1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Stephen W. Duffy
2Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom.
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Hemant M. Kocher
4Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Stephen P. Pereira
5Institute for Liver and Digestive Health, University College London, London, United Kingdom.
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Luisa Guarner (posthumous)
6Hospital General Universitari Vall Hebron, Barcelona, Spain.
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Cristiane Murta-Nascimento
7Hospital del Mar — Parc de Salut Mar, Barcelona, Spain.
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Francisco X. Real
8Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
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Núria Malats
8Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
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John Neoptolemos
9The NIHR Liverpool Pancreas Biomedical Research Unit, Liverpool, United Kingdom.
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Eithne Costello
9The NIHR Liverpool Pancreas Biomedical Research Unit, Liverpool, United Kingdom.
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William Greenhalf
9The NIHR Liverpool Pancreas Biomedical Research Unit, Liverpool, United Kingdom.
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Nick R. Lemoine
1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Tatjana Crnogorac-Jurcevic
1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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  • For correspondence: t.c.jurcevic@qmul.ac.uk
DOI: 10.1158/1078-0432.CCR-14-2467 Published August 2015
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ARTICLE USAGE: July 2015 to January 2021

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Total1397266993939

Cited By

Article Information

Volume 21, Issue 15, pp. 3512-3521

DOI 
https://doi.org/10.1158/1078-0432.CCR-14-2467
PubMed 
26240291

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received September 30, 2014
  • Revision received March 27, 2015
  • Accepted March 28, 2015
  • Published first August 2, 2015.

Copyright & Usage 
©2015 American Association for Cancer Research.

Author Information

  1. Tomasz P. Radon1,
  2. Nathalie J. Massat2,
  3. Richard Jones3,
  4. Wasfi Alrawashdeh1,
  5. Laurent Dumartin1,
  6. Darren Ennis1,
  7. Stephen W. Duffy2,
  8. Hemant M. Kocher4,
  9. Stephen P. Pereira5,
  10. Luisa Guarner (posthumous)6,
  11. Cristiane Murta-Nascimento7,
  12. Francisco X. Real8,
  13. Núria Malats8,
  14. John Neoptolemos9,
  15. Eithne Costello9,
  16. William Greenhalf9,
  17. Nick R. Lemoine1, and
  18. Tatjana Crnogorac-Jurcevic1,*
  1. 1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
  2. 2Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom.
  3. 3MS Bioworks, LLC, Ann Arbor, Michigan.
  4. 4Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
  5. 5Institute for Liver and Digestive Health, University College London, London, United Kingdom.
  6. 6Hospital General Universitari Vall Hebron, Barcelona, Spain.
  7. 7Hospital del Mar — Parc de Salut Mar, Barcelona, Spain.
  8. 8Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.
  9. 9The NIHR Liverpool Pancreas Biomedical Research Unit, Liverpool, United Kingdom.
  1. ↵*Corresponding Author:
    Tatjana Crnogorac-Jurcevic, Barts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK. Phone: 44-0-20-7882-3554; Fax: 44-0-20-7882-3884; E-mail: t.c.jurcevic{at}qmul.ac.uk
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Clinical Cancer Research: 21 (15)
August 2015
Volume 21, Issue 15
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Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma
Tomasz P. Radon, Nathalie J. Massat, Richard Jones, Wasfi Alrawashdeh, Laurent Dumartin, Darren Ennis, Stephen W. Duffy, Hemant M. Kocher, Stephen P. Pereira, Luisa Guarner (posthumous), Cristiane Murta-Nascimento, Francisco X. Real, Núria Malats, John Neoptolemos, Eithne Costello, William Greenhalf, Nick R. Lemoine and Tatjana Crnogorac-Jurcevic
Clin Cancer Res August 1 2015 (21) (15) 3512-3521; DOI: 10.1158/1078-0432.CCR-14-2467

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Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma
Tomasz P. Radon, Nathalie J. Massat, Richard Jones, Wasfi Alrawashdeh, Laurent Dumartin, Darren Ennis, Stephen W. Duffy, Hemant M. Kocher, Stephen P. Pereira, Luisa Guarner (posthumous), Cristiane Murta-Nascimento, Francisco X. Real, Núria Malats, John Neoptolemos, Eithne Costello, William Greenhalf, Nick R. Lemoine and Tatjana Crnogorac-Jurcevic
Clin Cancer Res August 1 2015 (21) (15) 3512-3521; DOI: 10.1158/1078-0432.CCR-14-2467
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