Skip to main content
  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

AACR logo

  • Register
  • Log in
  • My Cart
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • CCR Focus Archive
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Breast Cancer
      • Clinical Trials
      • Immunotherapy: Facts and Hopes
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

  • AACR Publications
    • Blood Cancer Discovery
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in
  • My Cart

Search

  • Advanced search
Clinical Cancer Research
Clinical Cancer Research
  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • CCR Focus Archive
    • Meeting Abstracts
    • Collections
      • COVID-19 & Cancer Resource Center
      • Breast Cancer
      • Clinical Trials
      • Immunotherapy: Facts and Hopes
      • Editors' Picks
      • "Best of" Collection
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • Editors' Picks
    • OnlineFirst
    • Citation
    • Author/Keyword
    • RSS Feeds
    • My Alert Summary & Preferences
  • News
    • Cancer Discovery News
  • COVID-19
  • Webinars
  • Search More

    Advanced Search

Table of Contents

Highlights

  • Highlights
    Highlights of This Issue
    Clin Cancer Res September 1 2015 21 (17) 3811-3811;

CCR 20th Anniversary Commentary

  • CCR 20th Anniversary Commentary | Free Article
    CCR 20th Anniversary Commentary: Triple-Negative Breast Cancer in 2015—Still in the Ballpark
    Steven A. Narod, Rebecca A. Dent and William D. Foulkes
    Clin Cancer Res September 1 2015 21 (17) 3813-3814; DOI:10.1158/1078-0432.CCR-14-3122

CCR Translations

  • CCR Translations
    Moving Beyond “Lumpology”: PET/CT Imaging of Pheochromocytoma and Paraganglioma
    Michael S. Hofman and Rodney J. Hicks
    Clin Cancer Res September 1 2015 21 (17) 3815-3817; DOI:10.1158/1078-0432.CCR-15-1073

  • CCR Translations
    Emerging Agents and New Mutations in EGFR-Mutant Lung Cancer
    Deborah Ayeni, Katerina Politi and Sarah B. Goldberg
    Clin Cancer Res September 1 2015 21 (17) 3818-3820; DOI:10.1158/1078-0432.CCR-15-1211

CCR New Strategies

  • CCR New Strategies
    New Strategies in Human Papillomavirus–Related Oropharynx Cancer: Effecting Advances in Treatment for a Growing Epidemic
    Erminia Massarelli, Renata Ferrarotto and Bonnie S. Glisson
    Clin Cancer Res September 1 2015 21 (17) 3821-3828; DOI:10.1158/1078-0432.CCR-14-1329

CCR Drug Updates

  • CCR Drug Updates
    Development of Olaparib for BRCA-Deficient Recurrent Epithelial Ovarian Cancer
    Krishnansu S. Tewari, Ramez N. Eskander and Bradley J. Monk
    Clin Cancer Res September 1 2015 21 (17) 3829-3835; DOI:10.1158/1078-0432.CCR-15-0088

Molecular Pathways

  • Molecular Pathways
    Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?
    D. Grahame Hardie
    Clin Cancer Res September 1 2015 21 (17) 3836-3840; DOI:10.1158/1078-0432.CCR-14-3300

Reviews

  • Reviews
    Using CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60
    William C. Reinhold, Margot Sunshine, Sudhir Varma, James H. Doroshow and Yves Pommier
    Clin Cancer Res September 1 2015 21 (17) 3841-3852; DOI:10.1158/1078-0432.CCR-15-0335

  • Reviews | AuthorChoice
    Refining the Mantle Cell Lymphoma Paradigm: Impact of Novel Therapies on Current Practice
    Irit Avivi and Andre Goy
    Clin Cancer Res September 1 2015 21 (17) 3853-3861; DOI:10.1158/1078-0432.CCR-15-0488

Cancer Therapy: Clinical

  • Cancer Therapy: Clinical | AuthorChoice
    A Randomized Phase II Trial of Sipuleucel-T with Concurrent versus Sequential Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer
    Eric J. Small, Raymond S. Lance, Thomas A. Gardner, Lawrence I. Karsh, Lawrence Fong, Candice McCoy, Todd DeVries, Nadeem A. Sheikh, Debraj GuhaThakurta, Nancy Chang, Charles H. Redfern and Neal D. Shore
    Clin Cancer Res September 1 2015 21 (17) 3862-3869; DOI:10.1158/1078-0432.CCR-15-0079

  • Cancer Therapy: Clinical
    First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors
    Alexander N. Starodub, Allyson J. Ocean, Manish A. Shah, Michael J. Guarino, Vincent J. Picozzi Jr, Linda T. Vahdat, Sajeve S. Thomas, Serengulam V. Govindan, Pius P. Maliakal, William A. Wegener, Steven A. Hamburger, Robert M. Sharkey and David M. Goldenberg
    Clin Cancer Res September 1 2015 21 (17) 3870-3878; DOI:10.1158/1078-0432.CCR-14-3321

  • Cancer Therapy: Clinical
    Vaccination with Melanoma Helper Peptides Induces Antibody Responses Associated with Improved Overall Survival
    Caroline M. Reed, Nicole D. Cresce, Ileana S. Mauldin, Craig L. Slingluff Jr and Walter C. Olson
    Clin Cancer Res September 1 2015 21 (17) 3879-3887; DOI:10.1158/1078-0432.CCR-15-0233

Personalized Medicine and Imaging

  • Personalized Medicine and Imaging
    Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma
    Ingo Janssen, Elise M. Blanchet, Karen Adams, Clara C. Chen, Corina M. Millo, Peter Herscovitch, David Taieb, Electron Kebebew, Hendrik Lehnert, Antonio T. Fojo and Karel Pacak
    Clin Cancer Res September 1 2015 21 (17) 3888-3895; DOI:10.1158/1078-0432.CCR-14-2751

  • Personalized Medicine and Imaging
    A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment
    Timothy H. Witney, Aileen Hoehne, Robert E. Reeves, Ohad Ilovich, Mohammad Namavari, Bin Shen, Frederick T. Chin, Jianghong Rao and Sanjiv S. Gambhir
    Clin Cancer Res September 1 2015 21 (17) 3896-3905; DOI:10.1158/1078-0432.CCR-14-3176

  • Personalized Medicine and Imaging
    MR-Guided Near-Infrared Spectral Tomography Increases Diagnostic Performance of Breast MRI
    Michael A. Mastanduno, Junqing Xu, Fadi El-Ghussein, Shudong Jiang, Hong Yin, Yan Zhao, Ke Wang, Fang Ren, Jiang Gui, Brian W. Pogue and Keith D. Paulsen
    Clin Cancer Res September 1 2015 21 (17) 3906-3912; DOI:10.1158/1078-0432.CCR-14-2546

Cancer Therapy: Preclinical

  • Cancer Therapy: Preclinical
    EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors
    Dalia Ercan, Hwan Geun Choi, Cai-Hong Yun, Marzia Capelletti, Ting Xie, Michael J. Eck, Nathanael S. Gray and Pasi A. Jänne
    Clin Cancer Res September 1 2015 21 (17) 3913-3923; DOI:10.1158/1078-0432.CCR-14-2789

  • Cancer Therapy: Preclinical | AuthorChoice
    The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment Strategies
    Matthew J. Niederst, Haichuan Hu, Hillary E. Mulvey, Elizabeth L. Lockerman, Angel R. Garcia, Zofia Piotrowska, Lecia V. Sequist and Jeffrey A. Engelman
    Clin Cancer Res September 1 2015 21 (17) 3924-3933; DOI:10.1158/1078-0432.CCR-15-0560

  • Cancer Therapy: Preclinical
    APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells
    Antonia Cagnetta, Irene Caffa, Chirag Acharya, Debora Soncini, Prakrati Acharya, Sophia Adamia, Ivana Pierri, Micaela Bergamaschi, Anna Garuti, Giulio Fraternali, Luca Mastracci, Alessandro Provenzani, Chiara Zucal, Gianluca Damonte, Annalisa Salis, Fabrizio Montecucco, Franco Patrone, Alberto Ballestrero, Santina Bruzzone, Marco Gobbi, Alessio Nencioni and Michele Cea
    Clin Cancer Res September 1 2015 21 (17) 3934-3945; DOI:10.1158/1078-0432.CCR-14-3023

  • Cancer Therapy: Preclinical
    MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma
    Suresh Mohan, Robert Vander Broek, Sujay Shah, Danielle F. Eytan, Matthew L. Pierce, Sophie G. Carlson, Jamie F. Coupar, Jialing Zhang, Hui Cheng, Zhong Chen and Carter Van Waes
    Clin Cancer Res September 1 2015 21 (17) 3946-3956; DOI:10.1158/1078-0432.CCR-14-3377

  • Cancer Therapy: Preclinical
    Untouched GMP-Ready Purified Engineered Immune Cells to Treat Cancer
    Trudy Straetemans, Cordula Gründer, Sabine Heijhuurs, Samantha Hol, Ineke Slaper-Cortenbach, Halvard Bönig, Zsolt Sebestyen and Jürgen Kuball
    Clin Cancer Res September 1 2015 21 (17) 3957-3968; DOI:10.1158/1078-0432.CCR-14-2860

Biology of Human Tumors

  • Biology of Human Tumors | AuthorChoice
    Differential Expression of Immune-Regulatory Genes Associated with PD-L1 Display in Melanoma: Implications for PD-1 Pathway Blockade
    Janis M. Taube, Geoffrey D. Young, Tracee L. McMiller, Shuming Chen, January T. Salas, Theresa S. Pritchard, Haiying Xu, Alan K. Meeker, Jinshui Fan, Chris Cheadle, Alan E. Berger, Drew M. Pardoll and Suzanne L. Topalian
    Clin Cancer Res September 1 2015 21 (17) 3969-3976; DOI:10.1158/1078-0432.CCR-15-0244

  • Biology of Human Tumors
    A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia
    Daniela F. Angelini, Tiziana Ottone, Gisella Guerrera, Serena Lavorgna, Michela Cittadini, Francesco Buccisano, Marco De Bardi, Francesca Gargano, Luca Maurillo, Mariadomenica Divona, Nélida I. Noguera, Maria Irno Consalvo, Giovanna Borsellino, Giorgio Bernardi, Sergio Amadori, Adriano Venditti, Luca Battistini and Francesco Lo-Coco
    Clin Cancer Res September 1 2015 21 (17) 3977-3985; DOI:10.1158/1078-0432.CCR-14-3186

  • Biology of Human Tumors
    Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas
    Esteban Braggio, Scott Van Wier, Juhi Ojha, Ellen McPhail, Yan W. Asmann, Jan Egan, Jackline Ayres da Silva, David Schiff, M. Beatriz Lopes, Paul A. Decker, Riccardo Valdez, Raoul Tibes, Bruce Eckloff, Thomas E. Witzig, A. Keith Stewart, Rafael Fonseca and Brian Patrick O'Neill
    Clin Cancer Res September 1 2015 21 (17) 3986-3994; DOI:10.1158/1078-0432.CCR-14-2116

  • Biology of Human Tumors | Free Article
    Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy
    Mario Giuliano, Huizhong Hu, Yen-Chao Wang, Xiaoyong Fu, Agostina Nardone, Sabrina Herrera, Sufeng Mao, Alejandro Contreras, Carolina Gutierrez, Tao Wang, Susan G. Hilsenbeck, Carmine De Angelis, Nicholas J. Wang, Laura M. Heiser, Joe W. Gray, Sara Lopez-Tarruella, Anne C. Pavlick, Meghana V. Trivedi, Gary C. Chamness, Jenny C. Chang, C. Kent Osborne, Mothaffar F. Rimawi and Rachel Schiff
    Clin Cancer Res September 1 2015 21 (17) 3995-4003; DOI:10.1158/1078-0432.CCR-14-2728

  • Biology of Human Tumors
    miR-663 Suppresses Oncogenic Function of CXCR4 in Glioblastoma
    Yu Shi, Cong Chen, Shi-Zhu Yu, Qing Liu, Jun Rao, Hua-Rong Zhang, Hua-Liang Xiao, Ti-Wei Fu, Hua Long, Zhi-Cheng He, Kai Zhou, Xiao-Hong Yao, You-Hong Cui, Xia Zhang, Yi-Fang Ping and Xiu-Wu Bian
    Clin Cancer Res September 1 2015 21 (17) 4004-4013; DOI:10.1158/1078-0432.CCR-14-2807

  • Biology of Human Tumors
    Induction of PD-L1 Expression by the EML4–ALK Oncoprotein and Downstream Signaling Pathways in Non–Small Cell Lung Cancer
    Keiichi Ota, Koichi Azuma, Akihiko Kawahara, Satoshi Hattori, Eiji Iwama, Junko Tanizaki, Taishi Harada, Koichiro Matsumoto, Koichi Takayama, Shinzo Takamori, Masayoshi Kage, Tomoaki Hoshino, Yoichi Nakanishi and Isamu Okamoto
    Clin Cancer Res September 1 2015 21 (17) 4014-4021; DOI:10.1158/1078-0432.CCR-15-0016

Letters to the Editor

  • Letters to the Editor
    To B(MP-2) or Not To B(MP-2): Cytokines and Tumor Surgery—Letter
    David S. Geller, Jonathan Gill, Michael Roth and Richard Gorlick
    Clin Cancer Res September 1 2015 21 (17) 4022-4022; DOI:10.1158/1078-0432.CCR-15-0470

  • Letters to the Editor
    To B(MP-2) or Not To B(MP-2): Cytokines and Tumor Surgery—Response
    Kurt R. Weiss
    Clin Cancer Res September 1 2015 21 (17) 4023-4023; DOI:10.1158/1078-0432.CCR-15-0875

Correction

  • Correction
    Correction: “Vertical” Inhibition of HER2 Yields Horizontal Gains in the Clinic
    Clin Cancer Res September 1 2015 21 (17) 4024-4024; DOI:10.1158/1078-0432.CCR-15-1662

Back to top
PreviousNext
Clinical Cancer Research: 21 (17)
September 2015
Volume 21, Issue 17
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover

Sign up for alerts

Issue Highlights

  • Induction of PD-L1 Expression by the EML4–ALK Oncoprotein and Downstream Signaling Pathways in Non–Small Cell Lung Cancer
  • Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma
  • First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors
  • A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment
  • MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma

Jump to

  • Highlights
  • CCR 20th Anniversary Commentary
  • CCR Translations
  • CCR New Strategies
  • CCR Drug Updates
  • Molecular Pathways
  • Reviews
  • Cancer Therapy: Clinical
  • Personalized Medicine and Imaging
  • Cancer Therapy: Preclinical
  • Biology of Human Tumors
  • Letters to the Editor
  • Correction
Advertisement
  • Most Cited
  • Most Read
Loading
  • scRNA-seq Analysis of Gastric Cancer TME
  • Toxicity Management Affects Checkpoint Inhibitor Efficacy
  • PDAC and GATA6 Expression
  • Rucaparib in mCRPC with a Non-BRCA DDR Gene Alteration
  • AR Gene Rearrangements in Prostate Cancer
More...
  • Home
  • Alerts
  • Feedback
  • Privacy Policy
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • CCR Focus Archive
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians

About Clinical Cancer Research

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2021 by the American Association for Cancer Research.

Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

Advertisement