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Volume 22, Issue 13, pp. 3286-3297
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History
- Received July 25, 2015
- Revision received January 12, 2016
- Accepted January 15, 2016
- Published first February 9, 2016.
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- Previous version (February 9, 2016 - 11:26).
- Previous version (April 20, 2016 - 09:36).
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©2016 American Association for Cancer Research.
Author Information
- Marina Bacac1,*,
- Tanja Fauti1,
- Johannes Sam1,
- Sara Colombetti1,
- Tina Weinzierl1,
- Djamila Ouaret2,
- Walter Bodmer2,
- Steffi Lehmann3,
- Thomas Hofer4,
- Ralf J. Hosse4,
- Ekkehard Moessner4,
- Oliver Ast4,
- Peter Bruenker4,
- Sandra Grau-Richards4,
- Teilo Schaller1,
- Annette Seidl5,
- Christian Gerdes1,
- Mario Perro1,
- Valeria Nicolini1,
- Nathalie Steinhoff1,
- Sherri Dudal6,
- Sebastian Neumann7,
- Thomas von Hirschheydt8,
- Christiane Jaeger4,
- Jose Saro9,
- Vaios Karanikas9,
- Christian Klein1, and
- Pablo Umaña1,*
- 1Oncology Discovery, Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, pRED, Zurich, Switzerland.
- 2Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
- 3Animal Imaging Center, Institute for Biomedical Engineering, ETH and University of Zurich, Zurich, Switzerland.
- 4Large Molecule Research, Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, pRED, Zurich, Switzerland.
- 5Roche Diagnostics GmbH, Penzberg, Germany.
- 6Pharmaceutical Sciences, Roche Innovation Center Basel, Basel, Switzerland.
- 7Global Technical Development Project Management, F. Hoffmann-La Roche AG, Basel, Switzerland.
- 8Large Molecule Research, Roche Innovation Center Penzberg, Germany.
- 9Translational Medicine, Roche Innovation Center Zurich, Zurich, Switzerland.
- ↵*Corresponding Authors:
Marina Bacac, Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Wagistrasse 18, Schlieren, Zurich 8952, Switzerland. Phone: 414-4755-6141; Fax: +41 44 755 61 60; E-mail: marina.bacac{at}roche.com; and Pablo Umaña, Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Wagistrasse 18, Schlieren, Zurich 8952, Switzerland. Phone: 414-4755-6141; Fax: +41 44 755 61 60; E-mail:Pablo.umana{at}roche.com
C. Klein and P. Umaña contributed equally to this article.
July 2016
Volume 22, Issue 13
Volume 22, Issue 13
A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors
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