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Clinical Cancer Research
Clinical Cancer Research

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About the Cover

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The cover shows a section of a liver tissue specimen from a patient with hepatocellular carcinoma. Immunohistochemical staining shows a reduced HNF-6 expression within tumor cells. For details, see the article by Sun and colleagues on page 502 of this issue.

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Clinical Cancer Research: 22 (2)
January 2016
Volume 22, Issue 2
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Issue Highlights

  • Krüppel-like Factor 4 Blocks Hepatocellular Carcinoma Dedifferentiation and Progression through Activation of Hepatocyte Nuclear Factor-6
  • Clinical and Translational Results of a Phase II, Randomized Trial of an Anti–IGF-1R (Cixutumumab) in Women with Breast Cancer That Progressed on Endocrine Therapy
  • Subtype-Specific Metagene-Based Prediction of Outcome after Neoadjuvant and Adjuvant Treatment in Breast Cancer
  • Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy
  • Enhanced Antitumor Activity of an Anti-5T4 Antibody–Drug Conjugate in Combination with PI3K/mTOR inhibitors or Taxanes
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Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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