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CCR Translations

Reimagining Vaccines for Prostate Cancer: Back to the Future

Eugene Shenderov and Emmanuel S. Antonarakis
Eugene Shenderov
1The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
2Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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  • ORCID record for Eugene Shenderov
Emmanuel S. Antonarakis
1The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
2Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland.
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  • For correspondence: eantona1@jhmi.edu
DOI: 10.1158/1078-0432.CCR-20-2257 Published October 2020
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Abstract

Given the modest clinical benefits observed with immune checkpoint blockade in advanced prostate cancer, there is a renewed interest in exploring other forms of immunotherapy. Here, the authors report the use of a novel plasmid DNA vaccine encoding the androgen receptor, called pTVG-AR, in men with metastatic hormone-sensitive prostate cancer.

See related article by Kyriakopoulos et al., p. 5162

Footnotes

  • Clin Cancer Res 2020;26:5056–8

  • Received June 30, 2020.
  • Revision received July 14, 2020.
  • Accepted July 29, 2020.
  • Published first July 31, 2020.
  • ©2020 American Association for Cancer Research.
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Clinical Cancer Research: 26 (19)
October 2020
Volume 26, Issue 19
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Reimagining Vaccines for Prostate Cancer: Back to the Future
Eugene Shenderov and Emmanuel S. Antonarakis
Clin Cancer Res October 1 2020 (26) (19) 5056-5058; DOI: 10.1158/1078-0432.CCR-20-2257

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Reimagining Vaccines for Prostate Cancer: Back to the Future
Eugene Shenderov and Emmanuel S. Antonarakis
Clin Cancer Res October 1 2020 (26) (19) 5056-5058; DOI: 10.1158/1078-0432.CCR-20-2257
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Clinical Cancer Research
eISSN: 1557-3265
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