Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA

Shuxiong Zeng; Yidie Ying; Naidong Xing; Baiyun Wang; Ziliang Qian; Zunlin Zhou; Zhensheng Zhang; Weidong Xu; Huiqing Wang; Lihe Dai; Li Gao; Tie Zhou; Jiatao Ji; Chuanliang Xu

doi:10.1158/1078-0432.CCR-20-0401

Precision Medicine and Imaging

Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA

Shuxiong Zeng, Yidie Ying, Naidong Xing, Baiyun Wang, Ziliang Qian, Zunlin Zhou, Zhensheng Zhang, Weidong Xu, Huiqing Wang, Lihe Dai, Li Gao, Tie Zhou, Jiatao Ji and Chuanliang Xu

Shuxiong Zeng

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Yidie Ying

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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ORCID record for Yidie Ying

Naidong Xing

2Department of Urology, Qilu Hospital of Shandong University, Jinan, Shandong, China.

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Baiyun Wang

3Suzhou Hongyuan Biotech Inc., Biobay, Suzhou, China.

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Ziliang Qian

3Suzhou Hongyuan Biotech Inc., Biobay, Suzhou, China.

4Prophet Genomics Inc., San Jose, California.

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Zunlin Zhou

2Department of Urology, Qilu Hospital of Shandong University, Jinan, Shandong, China.

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Zhensheng Zhang

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Weidong Xu

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Huiqing Wang

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Lihe Dai

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Li Gao

5Department of Pathology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Tie Zhou

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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Jiatao Ji

6Department of Urology, Shanghai Hudong Hospital, Pudong New Area, Shanghai, China.

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For correspondence: drxuchuanliang@126.com jijiatao22@163.com

Chuanliang Xu

1Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

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For correspondence: drxuchuanliang@126.com jijiatao22@163.com

DOI: 10.1158/1078-0432.CCR-20-0401 Published November 2020

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November 2020
Volume 26, Issue 21

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Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA

Shuxiong Zeng, Yidie Ying, Naidong Xing, Baiyun Wang, Ziliang Qian, Zunlin Zhou, Zhensheng Zhang, Weidong Xu, Huiqing Wang, Lihe Dai, Li Gao, Tie Zhou, Jiatao Ji and Chuanliang Xu

Clin Cancer Res November 1 2020 (26) (21) 5646-5654; DOI: 10.1158/1078-0432.CCR-20-0401

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Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA

Shuxiong Zeng, Yidie Ying, Naidong Xing, Baiyun Wang, Ziliang Qian, Zunlin Zhou, Zhensheng Zhang, Weidong Xu, Huiqing Wang, Lihe Dai, Li Gao, Tie Zhou, Jiatao Ji and Chuanliang Xu

Clin Cancer Res November 1 2020 (26) (21) 5646-5654; DOI: 10.1158/1078-0432.CCR-20-0401

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