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Clinical Cancer Research
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Translational Cancer Mechanisms and Therapy

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Adam J. Schoenfeld, Chai Bandlamudi, Jessica A. Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi, Jacklynn Egger, Carla P. Concepcion, Sonal Paul, Maria E. Arcila, Yahya Daneshbod, Jason Chang, Jennifer L. Sauter, Amanda Beras, Marc Ladanyi, Tyler Jacks, Charles M. Rudin, Barry S. Taylor, Mark T.A. Donoghue, Glenn Heller, Matthew D. Hellmann, Natasha Rekhtman and Gregory J. Riely
Adam J. Schoenfeld
1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
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  • ORCID record for Adam J. Schoenfeld
Chai Bandlamudi
2Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jessica A. Lavery
3Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • ORCID record for Jessica A. Lavery
Joseph Montecalvo
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Azadeh Namakydoust
1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
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Hira Rizvi
1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
5Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jacklynn Egger
5Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • ORCID record for Jacklynn Egger
Carla P. Concepcion
6David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
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Sonal Paul
7Department of Medicine, New York-Presbyterian Brooklyn Methodist Hospital - Weill Cornell Medicine, New York, New York.
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  • ORCID record for Sonal Paul
Maria E. Arcila
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Yahya Daneshbod
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jason Chang
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jennifer L. Sauter
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • ORCID record for Jennifer L. Sauter
Amanda Beras
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Marc Ladanyi
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Tyler Jacks
6David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
8Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts.
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Charles M. Rudin
1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
5Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York.
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Barry S. Taylor
2Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Mark T.A. Donoghue
2Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Glenn Heller
3Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
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Matthew D. Hellmann
1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
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Natasha Rekhtman
4Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • ORCID record for Natasha Rekhtman
  • For correspondence: rielyg@mskcc.org rekhtman@mskcc.org
Gregory J. Riely
1Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
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  • For correspondence: rielyg@mskcc.org rekhtman@mskcc.org
DOI: 10.1158/1078-0432.CCR-20-1825 Published November 2020
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Clinical Cancer Research: 26 (21)
November 2020
Volume 26, Issue 21
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The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer
Adam J. Schoenfeld, Chai Bandlamudi, Jessica A. Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi, Jacklynn Egger, Carla P. Concepcion, Sonal Paul, Maria E. Arcila, Yahya Daneshbod, Jason Chang, Jennifer L. Sauter, Amanda Beras, Marc Ladanyi, Tyler Jacks, Charles M. Rudin, Barry S. Taylor, Mark T.A. Donoghue, Glenn Heller, Matthew D. Hellmann, Natasha Rekhtman and Gregory J. Riely
Clin Cancer Res November 1 2020 (26) (21) 5701-5708; DOI: 10.1158/1078-0432.CCR-20-1825

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The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer
Adam J. Schoenfeld, Chai Bandlamudi, Jessica A. Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi, Jacklynn Egger, Carla P. Concepcion, Sonal Paul, Maria E. Arcila, Yahya Daneshbod, Jason Chang, Jennifer L. Sauter, Amanda Beras, Marc Ladanyi, Tyler Jacks, Charles M. Rudin, Barry S. Taylor, Mark T.A. Donoghue, Glenn Heller, Matthew D. Hellmann, Natasha Rekhtman and Gregory J. Riely
Clin Cancer Res November 1 2020 (26) (21) 5701-5708; DOI: 10.1158/1078-0432.CCR-20-1825
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Clinical Cancer Research
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