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Precision Medicine and Imaging

Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA

ChongFeng Gao, Luke Wisniewski, Ying Liu, Ben Staal, Ian Beddows, Dennis Plenker, Mohammed Aldakkak, Johnathan Hall, Daniel Barnett, Mirna Kheir Gouda, Peter Allen, Richard Drake, Amer Zureikat, Ying Huang, Douglas Evans, Aatur Singhi, Randall E. Brand, David A. Tuveson, Susan Tsai and Brian B. Haab
ChongFeng Gao
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Luke Wisniewski
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Ying Liu
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Ben Staal
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Ian Beddows
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Dennis Plenker
2Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
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Mohammed Aldakkak
3Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
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Johnathan Hall
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Daniel Barnett
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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Mirna Kheir Gouda
2Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
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Peter Allen
4Division of Surgical Oncology, Duke University School of Medicine, Durham, North Carolina.
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Richard Drake
5Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, South Carolina.
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Amer Zureikat
6Division of Gastrointestinal Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
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Ying Huang
7Division of Vaccine and Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, Washington.
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  • ORCID record for Ying Huang
Douglas Evans
3Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
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Aatur Singhi
6Division of Gastrointestinal Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
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Randall E. Brand
6Division of Gastrointestinal Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
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David A. Tuveson
2Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
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Susan Tsai
3Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
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Brian B. Haab
1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
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  • For correspondence: brian.haab@vai.org
DOI: 10.1158/1078-0432.CCR-20-2475 Published January 2021
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Article Information

Volume 27, Issue 1, pp. 226-236

DOI 
https://doi.org/10.1158/1078-0432.CCR-20-2475
PubMed 
33093149

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received June 24, 2020
  • Revision received August 17, 2020
  • Accepted October 13, 2020
  • Published first October 22, 2020.

Article Versions

  • Previous version (October 22, 2020 - 05:09).
  • Previous version (November 20, 2020 - 06:16).
  • Previous version (November 30, 2020 - 05:53).
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©2020 American Association for Cancer Research.

Author Information

  1. ChongFeng Gao1,
  2. Luke Wisniewski1,
  3. Ying Liu1,
  4. Ben Staal1,
  5. Ian Beddows1,
  6. Dennis Plenker2,
  7. Mohammed Aldakkak3,
  8. Johnathan Hall1,
  9. Daniel Barnett1,
  10. Mirna Kheir Gouda2,
  11. Peter Allen4,
  12. Richard Drake5,
  13. Amer Zureikat6,
  14. Ying Huang7,
  15. Douglas Evans3,
  16. Aatur Singhi6,
  17. Randall E. Brand6,
  18. David A. Tuveson2,
  19. Susan Tsai3, and
  20. Brian B. Haab1,*
  1. 1Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
  2. 2Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  3. 3Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
  4. 4Division of Surgical Oncology, Duke University School of Medicine, Durham, North Carolina.
  5. 5Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, South Carolina.
  6. 6Division of Gastrointestinal Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
  7. 7Division of Vaccine and Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  1. ↵*Corresponding Author:
    Brian B. Haab, Van Andel Institute, 333 Bostwick NE, Grand Rapids, MI 49503. Phone: 616-234-5268; Fax: 616-234-5269; E-mail: brian.haab{at}vai.org
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Clinical Cancer Research: 27 (1)
January 2021
Volume 27, Issue 1
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Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA
ChongFeng Gao, Luke Wisniewski, Ying Liu, Ben Staal, Ian Beddows, Dennis Plenker, Mohammed Aldakkak, Johnathan Hall, Daniel Barnett, Mirna Kheir Gouda, Peter Allen, Richard Drake, Amer Zureikat, Ying Huang, Douglas Evans, Aatur Singhi, Randall E. Brand, David A. Tuveson, Susan Tsai and Brian B. Haab
Clin Cancer Res January 1 2021 (27) (1) 226-236; DOI: 10.1158/1078-0432.CCR-20-2475

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Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA
ChongFeng Gao, Luke Wisniewski, Ying Liu, Ben Staal, Ian Beddows, Dennis Plenker, Mohammed Aldakkak, Johnathan Hall, Daniel Barnett, Mirna Kheir Gouda, Peter Allen, Richard Drake, Amer Zureikat, Ying Huang, Douglas Evans, Aatur Singhi, Randall E. Brand, David A. Tuveson, Susan Tsai and Brian B. Haab
Clin Cancer Res January 1 2021 (27) (1) 226-236; DOI: 10.1158/1078-0432.CCR-20-2475
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