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Table of Contents

Highlights

CCR Translations

CCR Perspectives in Regulatory Science and Policy

CCR Drug Updates

Perspectives

Research Briefs: Clinical Trial Brief Report

  • Research Briefs: Clinical Trial Brief Report
    A Randomized Phase IIb Study of Low-dose Tamoxifen in Chest-irradiated Cancer Survivors at Risk for Breast Cancer
    Smita Bhatia, Melanie R. Palomares, Lindsey Hageman, Yanjun Chen, Wendy Landier, Kandice Smith, Heidi Umphrey, Caroline A. Reich, Kathryn W. Zamora, Saro H. Armenian, Therese B. Bevers, Anne Blaes, Tara Henderson, David Hodgson, Melissa M. Hudson, Larissa A. Korde, Susan A. Melin, Sofia D. Merajver, Linda Overholser, Sandhya Pruthi, F. Lennie Wong and Judy E. Garber
    Clin Cancer Res February 15 2021 27 (4) 967-974; DOI:10.1158/1078-0432.CCR-20-3609

Clinical Trials: Targeted Therapy

Clinical Trials: Immunotherapy

Precision Medicine and Imaging

  • Precision Medicine and Imaging | AuthorChoice
    Molecular Imaging of Chimeric Antigen Receptor T Cells by ICOS-ImmunoPET
    Federico Simonetta, Israt S. Alam, Juliane K. Lohmeyer, Bita Sahaf, Zinaida Good, Weiyu Chen, Zunyu Xiao, Toshihito Hirai, Lukas Scheller, Pujan Engels, Ophir Vermesh, Elise Robinson, Tom Haywood, Ataya Sathirachinda, Jeanette Baker, Meena B. Malipatlolla, Liora M. Schultz, Jay Y. Spiegel, Jason T. Lee, David B. Miklos, Crystal L. Mackall, Sanjiv S. Gambhir and Robert S. Negrin
    Clin Cancer Res February 15 2021 27 (4) 1058-1068; DOI:10.1158/1078-0432.CCR-20-2770

  • Precision Medicine and Imaging
    Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer
    Sara A. Väyrynen, Jinming Zhang, Chen Yuan, Juha P. Väyrynen, Andressa Dias Costa, Hannah Williams, Vicente Morales-Oyarvide, Mai Chan Lau, Douglas A. Rubinson, Richard F. Dunne, Margaret M. Kozak, Wenjia Wang, Diana Agostini-Vulaj, Michael G. Drage, Lauren Brais, Emma Reilly, Osama Rahma, Thomas Clancy, Jiping Wang, David C. Linehan, Andrew J. Aguirre, Charles S. Fuchs, Lisa M. Coussens, Daniel T. Chang, Albert C. Koong, Aram F. Hezel, Shuji Ogino, Jonathan A. Nowak and Brian M. Wolpin
    Clin Cancer Res February 15 2021 27 (4) 1069-1081; DOI:10.1158/1078-0432.CCR-20-3141

  • Precision Medicine and Imaging
    Defining the Comprehensive Genomic Landscapes of Pancreatic Ductal Adenocarcinoma Using Real-World Endoscopic Aspiration Samples
    Alexander Semaan, Vincent Bernard, Jaewon J. Lee, Justin W. Wong, Jonathan Huang, Daniel B. Swartzlander, Bret M. Stephens, Maria E. Monberg, Brian R. Weston, Manoop S. Bhutani, Kyle Chang, Paul A. Scheet, Anirban Maitra, Yasminka A. Jakubek and Paola A. Guerrero
    Clin Cancer Res February 15 2021 27 (4) 1082-1093; DOI:10.1158/1078-0432.CCR-20-2667

  • Precision Medicine and Imaging
    Discrimination of Breast Cancer from Healthy Breast Tissue Using a Three-component Diffusion-weighted MRI Model
    Maren M. Sjaastad Andreassen, Ana E. Rodríguez-Soto, Christopher C. Conlin, Igor Vidić, Tyler M. Seibert, Anne M. Wallace, Somaye Zare, Joshua Kuperman, Boya Abudu, Grace S. Ahn, Michael Hahn, Neil P. Jerome, Agnes Østlie, Tone F. Bathen, Haydee Ojeda-Fournier, Pål Erik Goa, Rebecca Rakow-Penner and Anders M. Dale
    Clin Cancer Res February 15 2021 27 (4) 1094-1104; DOI:10.1158/1078-0432.CCR-20-2017

  • Precision Medicine and Imaging
    Genomic Characterization of de novo Metastatic Breast Cancer
    Ana C. Garrido-Castro, Liam F. Spurr, Melissa E. Hughes, Yvonne Y. Li, Andrew D. Cherniack, Priti Kumari, Maxwell R. Lloyd, Brittany Bychkovsky, Romualdo Barroso-Sousa, Simona Di Lascio, Esha Jain, Janet Files, Ayesha Mohammed-Abreu, Max Krevalin, Colin MacKichan, William T. Barry, Hao Guo, Daniel Xia, Ethan Cerami, Barrett J. Rollins, Laura E. MacConaill, Neal I. Lindeman, Ian E. Krop, Bruce E. Johnson, Nikhil Wagle, Eric P. Winer, Deborah A. Dillon and Nancy U. Lin
    Clin Cancer Res February 15 2021 27 (4) 1105-1118; DOI:10.1158/1078-0432.CCR-20-1720

  • Precision Medicine and Imaging | AuthorChoice
    Early Adaptation of Colorectal Cancer Cells to the Peritoneal Cavity Is Associated with Activation of “Stemness” Programs and Local Inflammation
    Jorge Barriuso, Raghavendar T. Nagaraju, Shreya Belgamwar, Bipasha Chakrabarty, George J. Burghel, Helene Schlecht, Lucy Foster, Elaine Kilgour, Andrew J. Wallace, Michael Braun, Caroline Dive, D. Gareth Evans, Robert G. Bristow, Mark P. Saunders, Sarah T. O'Dwyer and Omer Aziz
    Clin Cancer Res February 15 2021 27 (4) 1119-1130; DOI:10.1158/1078-0432.CCR-20-3320

  • Precision Medicine and Imaging
    Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains
    Sebastian Klein, Alexander Quaas, Jennifer Quantius, Heike Löser, Jörn Meinel, Martin Peifer, Steffen Wagner, Stefan Gattenlöhner, Claus Wittekindt, Magnus von Knebel Doeberitz, Elena-Sophie Prigge, Christine Langer, Ka-Won Noh, Margaret Maltseva, Hans Christian Reinhardt, Reinhard Büttner, Jens Peter Klussmann and Nora Wuerdemann
    Clin Cancer Res February 15 2021 27 (4) 1131-1138; DOI:10.1158/1078-0432.CCR-20-3596

Translational Cancer Mechanisms and Therapy

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