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Clinical Cancer Research

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Table of Contents

Advances in Brief

  • Advances in Brief
    Expression of Transforming Growth Factor β Type II Receptors in Head and Neck Squamous Cell Carcinoma
    Carlos A. Muro-Cacho, Meredith Anderson, Joehassin Cordero and Teresita Muñoz-Antonia
    Clin Cancer Res June 1 1999 5 (6) 1243-1248;

  • Advances in Brief
    Reduction of BRCA1 Protein Expression in Japanese Sporadic Breast Carcinomas and Its Frequent Loss in BRCA1-associated Cases
    Kiyotsugu Yoshikawa, Kazuo Honda, Takashi Inamoto, Hisashi Shinohara, Akira Yamauchi, Kenji Suga, Takazo Okuyama, Toshihide Shimada, Hiroshi Kodama, Shinzaburo Noguchi, Adi F. Gazdar, Yoshio Yamaoka and Rei Takahashi
    Clin Cancer Res June 1 1999 5 (6) 1249-1261;

  • Advances in Brief
    Spontaneous ex Vivo Apoptosis of Peripheral Blood Mononuclear Cells in Patients with Head and Neck Cancer
    Takao Saito, Iris Kuss, Grzegorz Dworacki, William Gooding, Jonas T. Johnson and Theresa L. Whiteside
    Clin Cancer Res June 1 1999 5 (6) 1263-1273;

  • Advances in Brief
    Detection of Subclinical Cancers by Prostate-specific Antigen Screening in Asymptomatic Men from High-Risk Prostate Cancer Families
    Mika P. Matikainen, Johanna Schleutker, Pertti Mörsky, Olli-P. Kallioniemi and Teuvo L. J. Tammela
    Clin Cancer Res June 1 1999 5 (6) 1275-1279;

  • Advances in Brief
    Generation of Anti-p53 Cytotoxic T Lymphocytes from Human Peripheral Blood Using Autologous Dendritic Cells
    Kazuaki Chikamatsu, Koji Nakano, Walter J. Storkus, Ettore Appella, Michael T. Lotze, Theresa L. Whiteside and Albert B. DeLeo
    Clin Cancer Res June 1 1999 5 (6) 1281-1288;

Clinical Trials

  • Clinical Trials
    Generation of Immunity to the HER-2/neu Oncogenic Protein in Patients with Breast and Ovarian Cancer Using a Peptide-based Vaccine
    Mary L. Disis, Kenneth H. Grabstein, Paul R. Sleath and Martin A. Cheever
    Clin Cancer Res June 1 1999 5 (6) 1289-1297;

  • Clinical Trials
    A Phase I Study of Continuous Infusion Doxorubicin and Paclitaxel Chemotherapy with Granulocyte Colony-Stimulating Factor for Relapsed Epithelial Ovarian Cancer
    Linda R. Duska, Richard Penson, Jeffrey G. Supko, Dianne M. Finkelstein, Thomas Makastorsis, Joan Gallagher, Karen Borden, Annekathryn Goodman, Arlan F. Fuller, Najmosama Nikrui and Michael V. Seiden
    Clin Cancer Res June 1 1999 5 (6) 1299-1305;

  • Clinical Trials
    Rhenium-186-labeled Hydroxyethylidene Diphosphonate Dosimetry and Dosing Guidelines for the Palliation of Skeletal Metastases from Androgen-independent Prostate Cancer
    Martin C. Graham, Howard I. Scher, Gen-Bao Liu, Samuel D-J. Yeh, Tracy Curley, Farhad Daghighian, Stanley J. Goldsmith and Steven M. Larson
    Clin Cancer Res June 1 1999 5 (6) 1307-1318;

  • Clinical Trials
    Long Survival of Patients with Small Cell Lung Cancer after Adjuvant Treatment with the Anti-Idiotypic Antibody BEC2 Plus Bacillus Calmette-Guérin
    Stefan C. Grant, Mark G. Kris, Alan N. Houghton and Paul B. Chapman
    Clin Cancer Res June 1 1999 5 (6) 1319-1323;

  • Clinical Trials
    Pharmacokinetics and Pharmacodynamics of 9-Aminocamptothecin Infused Over 72 Hours in Phase II Studies
    Hironobu Minami, Thomas E. Lad, M. Kelly Nicholas, Everett E. Vokes and Mark J. Ratain
    Clin Cancer Res June 1 1999 5 (6) 1325-1330;

  • Clinical Trials
    A Phase I Study of Active Immunotherapy with Carcinoembryonic Antigen Peptide (CAP-1)-pulsed, Autologous Human Cultured Dendritic Cells in Patients with Metastatic Malignancies Expressing Carcinoembryonic Antigen
    Michael A. Morse, Yuping Deng, Doris Coleman, Shelley Hull, Eva Kitrell-Fisher, Smita Nair, Jeffrey Schlom, Mary-Ellen Ryback and H. Kim Lyerly
    Clin Cancer Res June 1 1999 5 (6) 1331-1338;

  • Clinical Trials
    A Phase I Trial of Calcitriol (1,25-Dihydroxycholecalciferol) in Patients with Advanced Malignancy
    David C. Smith, Candace S. Johnson, Catherine C. Freeman, Josephia Muindi, John W. Wilson and Donald L. Trump
    Clin Cancer Res June 1 1999 5 (6) 1339-1345;

  • Clinical Trials
    High Inter- and Intrapatient Variation in 5-Fluorouracil Plasma Concentrations during a Prolonged Drug Infusion
    Chris H. Takimoto, Lorrin K. Yee, David J. Venzon, Barbara Schuler, Frank Grollman, Chetin Chabuk, J. Michael Hamilton, Alice P. Chen, Carmen J. Allegra and Jean L. Grem
    Clin Cancer Res June 1 1999 5 (6) 1347-1352;

  • Clinical Trials
    Immunogenicity of Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Products in Patients Undergoing Combination Therapy with GM-CSF
    Meenu Wadhwa, Anna-Lena Hjelm Skog, Chris Bird, Peter Ragnhammar, Maria Lilljefors, Rose Gaines-Das, Hakan Mellstedt and Robin Thorpe
    Clin Cancer Res June 1 1999 5 (6) 1353-1361;

  • Clinical Trials
    Phase I Study of Transforming Growth Factor-β3 Mouthwashes for Prevention of Chemotherapy-induced Mucositis
    A. N. Machteld Wymenga, Winette T. A. van der Graaf, Lieuwe S. Hofstra, Fred K. L. Spijkervet, Wim Timens, Hetty Timmer-Bosscha, Wim J. Sluiter, A. H. J. A. W. van Buuren, Nanno H. Mulder and Elisabeth G. E. de Vries
    Clin Cancer Res June 1 1999 5 (6) 1363-1368;

Molecular Oncology, Markers, Clinical Correlates

  • Molecular Oncology, Markers, Clinical Correlates
    Expression of Proinflammatory and Proangiogenic Cytokines in Patients with Head and Neck Cancer
    Zhong Chen, Pramit S. Malhotra, Giovana R. Thomas, Frank G. Ondrey, Dianne C. Duffey, Conrad W. Smith, Ileana Enamorado, Ning T. Yeh, Glenn S. Kroog, Susan Rudy, Linda McCullagh, Shaker Mousa, Matha Quezado, Laurie L. Herscher and Carter Van Waes
    Clin Cancer Res June 1 1999 5 (6) 1369-1379;

  • Molecular Oncology, Markers, Clinical Correlates
    Detection of erbB-2 Amplifications in Tumors and Sera from Esophageal Carcinoma Patients
    Pei-Wen Chiang, David G. Beer, Wan-Li Wei, Mark B. Orringer and David M. Kurnit
    Clin Cancer Res June 1 1999 5 (6) 1381-1386;

  • Molecular Oncology, Markers, Clinical Correlates
    Absence of PTEN Germ-Line Mutations in Men with a Potential Inherited Predisposition to Prostate Cancer
    Kathleen A. Cooney, Hui C. Tsou, Elizabeth M. Petty, Susan Miesfeldt, Xiao Li Ping, Alexandra C. Gruener and Monica Peacocke
    Clin Cancer Res June 1 1999 5 (6) 1387-1391;

  • Molecular Oncology, Markers, Clinical Correlates
    Antinuclear Antibodies as Potential Markers of Lung Cancer
    Félix Fernández-Madrid, Pamela J. VandeVord, Xin Yang, Robert L. Karvonen, Pippa M. Simpson, Michael J. Kraut, José L. Granda and John E. Tomkiel
    Clin Cancer Res June 1 1999 5 (6) 1393-1400;

  • Molecular Oncology, Markers, Clinical Correlates
    Rearrangements of Chromosome Band 1p36 in Non-Hodgkin’s Lymphoma
    Bhavana J. Dave, Michelle M. Hess, Diane L. Pickering, Dianna H. Zaleski, Andrea L. Pfeifer, Dennis D. Weisenburger, James O. Armitage and Warren G. Sanger
    Clin Cancer Res June 1 1999 5 (6) 1401-1409;

  • Molecular Oncology, Markers, Clinical Correlates
    Enhanced Expression of Inducible Nitric Oxide Synthase and Nitrotyrosine in Gastric Mucosa of Gastric Cancer Patients
    Toyoko Goto, Ken Haruma, Yasuhiko Kitadai, Masanori Ito, Masaharu Yoshihara, Koji Sumii, Norihiko Hayakawa and Goro Kajiyama
    Clin Cancer Res June 1 1999 5 (6) 1411-1415;

  • Molecular Oncology, Markers, Clinical Correlates
    Loss of Heterozygosity Accumulation in Primary Breast Carcinomas and Additionally in Corresponding Distant Metastases Is Associated with Poor Outcome
    Monika Hampl, Jürgen A. Hampl, Gilfe Reiss, Gabriele Schackert, Hans-D. Saeger and Hans K. Schackert
    Clin Cancer Res June 1 1999 5 (6) 1417-1425;

  • Molecular Oncology, Markers, Clinical Correlates
    Prognostic Value of Circulating Soluble E-Selectin Concentrations in Node-negative Breast Cancer Patients
    Mohamed Hebbar, Françcoise Révillion, Marie-Michèle Louchez, Charles Fournier, Jacques Bonneterre and Jean-Philippe Peyrat
    Clin Cancer Res June 1 1999 5 (6) 1427-1433;

  • Molecular Oncology, Markers, Clinical Correlates
    Chromosomal Abnormalities in Glioblastoma Multiforme by Comparative Genomic Hybridization: Correlation with Radiation Treatment Outcome
    Stephen L. Huhn, Gayatry Mohapatra, Andrew Bollen, Kathleen Lamborn, Michael D. Prados and Burt G. Feuerstein
    Clin Cancer Res June 1 1999 5 (6) 1435-1443;

  • Molecular Oncology, Markers, Clinical Correlates
    Infrequent Germ-line Mutation of the E-cadherin Gene in Japanese Familial Gastric Cancer Kindreds
    Satoru Iida, Yoshimitsu Akiyama, Wataru Ichikawa, Toshiki Yamashita, Tadashi Nomizu, Zenro Nihei, Kenichi Sugihara and Yasuhito Yuasa
    Clin Cancer Res June 1 1999 5 (6) 1445-1447;

  • Molecular Oncology, Markers, Clinical Correlates
    The Prognostic Significance of Tumor-associated Antigen 22-1-1 Expression in Adenocarcinoma of the Uterine Cervix
    Tsunehisa Kaku, Kenzo Sonoda, Toshiharu Kamura, Toshio Hirakawa, Kunihiro Sakai, Satoshi Amada, Shinji Ogawa, Hiroaki Kobayashi, Manabu Nakashima, Takeshi Watanabe and Hitoo Nakano
    Clin Cancer Res June 1 1999 5 (6) 1449-1453;

  • Molecular Oncology, Markers, Clinical Correlates
    Differential Expression of the Retinoblastoma Gene Family Members in Choroidal Melanoma: Prognostic Significance
    Mina Massaro-Giordano, Gianluca Baldi, Antonio De Luca, Alfonso Baldi and Antonio Giordano
    Clin Cancer Res June 1 1999 5 (6) 1455-1458;

  • Molecular Oncology, Markers, Clinical Correlates
    Biological Characterization of Subgroups of Squamous Cell Lung Carcinomas
    Jürgen Mattern, Reet Koomägi and Manfred Volm
    Clin Cancer Res June 1 1999 5 (6) 1459-1463;

  • Molecular Oncology, Markers, Clinical Correlates
    Expression of the 67-kDa Laminin Receptor in Acute Myeloid Leukemia Cells Mediates Adhesion to Laminin and Is Frequently Associated with Monocytic Differentiation
    Nunzia Montuori, Carmine Selleri, Antonio Maria Risitano, Anna Maria Raiola, Pia Ragno, Luigi Del Vecchio, Bruno Rotoli and Guido Rossi
    Clin Cancer Res June 1 1999 5 (6) 1465-1472;

  • Molecular Oncology, Markers, Clinical Correlates
    Increased Serum and Urinary Levels of a Parathyroid Hormone-related Protein COOH Terminus in Non-Small Cell Lung Cancer Patients
    Yutaka Nishigaki, Yoshinobu Ohsaki, Eri Toyoshima and Kenjiro Kikuchi
    Clin Cancer Res June 1 1999 5 (6) 1473-1481;

  • Molecular Oncology, Markers, Clinical Correlates
    Human Telomerase Reverse Transcriptase (hTERT) Gene Expression in Thyroid Neoplasms
    Motoyasu Saji, Steve Xydas, William H. Westra, Chien-Ko Liang, Douglas P. Clark, Robert Udelsman, Christopher B. Umbricht, Saraswati Sukumar and Martha A. Zeiger
    Clin Cancer Res June 1 1999 5 (6) 1483-1489;

  • Molecular Oncology, Markers, Clinical Correlates
    High-Level Expression of EPHB6, EFNB2, and EFNB3 Is Associated with Low Tumor Stage and High TrkA Expression in Human Neuroblastomas
    Xao X. Tang, Audrey E. Evans, Huaqing Zhao, Avital Cnaan, Wendy London, Susan L. Cohn, Garrett M. Brodeur and Naohiko Ikegaki
    Clin Cancer Res June 1 1999 5 (6) 1491-1496;

  • Molecular Oncology, Markers, Clinical Correlates
    Messenger RNA Determination of Estrogen Receptor, Progesterone Receptor, pS2, and Plasminogen Activator Inhibitor-1 by Competitive Reverse Transcription-Polymerase Chain Reaction in Human Breast Cancer
    Dan Tong, Christian Schneeberger, Klaus Czerwenka, Rita K. Schmutzler, Paul Speiser, Elisabeth Kucera, Nicole Concin, Ernst Kubista, Sepp Leodolter and Robert Zeillinger
    Clin Cancer Res June 1 1999 5 (6) 1497-1502;

  • Molecular Oncology, Markers, Clinical Correlates
    Decreased Expression of Retinoic Acid Receptors, Transforming Growth Factor β, Involucrin, and Cornifin in Cervical Intraepithelial Neoplasia
    Xiao-Chun Xu, Michele F. Mitchell, Elvio Silva, Anton Jetten and Reuben Lotan
    Clin Cancer Res June 1 1999 5 (6) 1503-1508;

Experimental Therapeutics, Preclinical Pharmacology

  • Experimental Therapeutics, Preclinical Pharmacology
    Phenylbutyrate Induces Cell Differentiation and Modulates Epstein-Barr Virus Gene Expression in Burkitt’s Lymphoma Cells
    Matia Bar-Ner, Alain Thibault, Maria Tsokos, Ian T. Magrath and Dvorit Samid
    Clin Cancer Res June 1 1999 5 (6) 1509-1516;

  • Experimental Therapeutics, Preclinical Pharmacology
    Ionizing Radiation Improves Survival in Mice Bearing Intracranial High-Grade Gliomas Injected with Genetically Modified Herpes Simplex Virus
    Jeffrey D. Bradley, Yasushi Kataoka, Sunil Advani, Su Mi Chung, Ramin B. Arani, G. Yancey Gillespie, Richard J. Whitley, James M. Markert, Bernard Roizman and Ralph R. Weichselbaum
    Clin Cancer Res June 1 1999 5 (6) 1517-1522;

  • Experimental Therapeutics, Preclinical Pharmacology
    Use of Carrier Cells to Deliver a Replication-selective Herpes Simplex Virus-1 Mutant for the Intraperitoneal Therapy of Epithelial Ovarian Cancer
    George Coukos, Antonis Makrigiannakis, Eugene H. Kang, David Caparelli, Ivor Benjamin, Larry R. Kaiser, Stephen C. Rubin, Steven M. Albelda and Katherine L. Molnar-Kimber
    Clin Cancer Res June 1 1999 5 (6) 1523-1537;

  • Experimental Therapeutics, Preclinical Pharmacology
    125I-labeled Anti-Epidermal Growth Factor Receptor-vIII Single-Chain Fv Exhibits Specific and High-Level Targeting of Glioma Xenografts
    Chien-Tsun Kuan, Craig J. Reist, Catherine F. Foulon, Ian A. J. Lorimer, Gary Archer, Charles N. Pegram, Ira Pastan, Michael R. Zalutsky and Darell D. Bigner
    Clin Cancer Res June 1 1999 5 (6) 1539-1549;

  • Experimental Therapeutics, Preclinical Pharmacology
    Combination Surgery and Nonviral Interleukin 2 Gene Therapy for Head and Neck Cancer
    Daqing Li, Wen Jiang, Jeffery S. Bishop, Robert Ralston and Bert W. O’Malley Jr.
    Clin Cancer Res June 1 1999 5 (6) 1551-1556;

  • Experimental Therapeutics, Preclinical Pharmacology
    Purging of Contaminating Breast Cancer Cells from Hematopoietic Stem Cell Grafts by Adenoviral GAL-TEK Gene Therapy and Magnetic Antibody Cell Separation
    Frank C. Marini, Virginia Snell, Qingnan Yu, Xin Zhang, S. Eva Singletary, Richard Champlin and Michael Andreeff
    Clin Cancer Res June 1 1999 5 (6) 1557-1568;

  • Experimental Therapeutics, Preclinical Pharmacology
    Structure-based Design of Specific Inhibitors of Janus Kinase 3 as Apoptosis-inducing Antileukemic Agents
    Elise A. Sudbeck, Xing-Ping Liu, Rama Krishna Narla, Sandeep Mahajan, Sutapa Ghosh, Chen Mao and Fatih M. Uckun
    Clin Cancer Res June 1 1999 5 (6) 1569-1582;

  • Experimental Therapeutics, Preclinical Pharmacology
    Penetration of Anticancer Drugs through Solid Tissue: A Factor That Limits the Effectiveness of Chemotherapy for Solid Tumors
    Jonathan K. Tunggal, David S. M. Cowan, Hafsa Shaikh and Ian F. Tannock
    Clin Cancer Res June 1 1999 5 (6) 1583-1586;

  • Experimental Therapeutics, Preclinical Pharmacology
    Vitronectin, a Glioma-derived Extracellular Matrix Protein, Protects Tumor Cells from Apoptotic Death
    Joon H. Uhm, Nora P. Dooley, Athanassios P. Kyritsis, Jasti S. Rao and Candece L. Gladson
    Clin Cancer Res June 1 1999 5 (6) 1587-1594;

Cancer Biology, Immunology, Cytokines

  • Cancer Biology, Immunology, Cytokines
    CLAR1, a Novel Gene That Exhibits Enhanced Expression in Advanced Human Prostate Cancer
    Rachel H. Rondinelli and James V. Tricoli
    Clin Cancer Res June 1 1999 5 (6) 1595-1602;

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June 1999
Volume 5, Issue 6
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Clinical Cancer Research
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