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Clinical Trials

Effect of Hepatic Dysfunction due to Liver Metastases on the Pharmacokinetics of Capecitabine and Its Metabolites

Chris Twelves, Robert Glynne-Jones, Jim Cassidy, Johannes Schüller, Timothy Goggin, Brigitte Roos, Ludger Banken, Masahiro Utoh, Erhard Weidekamm and Bruno Reigner
Chris Twelves
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Robert Glynne-Jones
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Jim Cassidy
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Johannes Schüller
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Timothy Goggin
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Brigitte Roos
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Ludger Banken
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Masahiro Utoh
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Erhard Weidekamm
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Bruno Reigner
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DOI:  Published July 1999
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Article Information

Volume 5, Issue 7, pp. 1696-1702

PubMed 
10430071

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Accepted March 22, 1999
  • Received August 19, 1999
  • Revision received March 19, 1999
  • Published first July 1, 1999.

Copyright & Usage 
© 1999

Author Information

  1. Chris Twelves,
  2. Robert Glynne-Jones,
  3. Jim Cassidy,
  4. Johannes Schüller,
  5. Timothy Goggin,
  6. Brigitte Roos,
  7. Ludger Banken,
  8. Masahiro Utoh,
  9. Erhard Weidekamm and
  10. Bruno Reigner1
  1. Beatson Oncology Centre, Western Infirmary, Glasgow, United Kingdom [C. T.]; Departments of Clinical Pharmacology [B. Ro., B. Re., T. G., E. W.] and Biostatistics [L. B.], F. Hoffmann-La Roche Ltd, CH-4070 Basel, Switzerland; Nippon Roche Research Center, Kamakura, Japan [M. U.]; Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen, United Kingdom [J. C.]; Mount Vernon Hospital, London, United Kingdom [R. G-J.]; and Hospital Rudolfstiftung, Vienna, Austria [J. S.]
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    July 1999
    Volume 5, Issue 7
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    Effect of Hepatic Dysfunction due to Liver Metastases on the Pharmacokinetics of Capecitabine and Its Metabolites
    Chris Twelves, Robert Glynne-Jones, Jim Cassidy, Johannes Schüller, Timothy Goggin, Brigitte Roos, Ludger Banken, Masahiro Utoh, Erhard Weidekamm and Bruno Reigner
    Clin Cancer Res July 1 1999 (5) (7) 1696-1702;

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    Effect of Hepatic Dysfunction due to Liver Metastases on the Pharmacokinetics of Capecitabine and Its Metabolites
    Chris Twelves, Robert Glynne-Jones, Jim Cassidy, Johannes Schüller, Timothy Goggin, Brigitte Roos, Ludger Banken, Masahiro Utoh, Erhard Weidekamm and Bruno Reigner
    Clin Cancer Res July 1 1999 (5) (7) 1696-1702;
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