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Clinical Cancer Research
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Clinical Trials: Immunotherapy

Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma

Lakshmi Nayak, Annette M. Molinaro, Katherine Peters, Jennifer L. Clarke, Justin T. Jordan, John de Groot, Leia Nghiemphu, Thomas Kaley, Howard Colman, Christine McCluskey, Sarah Gaffey, Timothy R. Smith, David J. Cote, Mariano Severgnini, Jennifer H. Yearley, Qing Zhao, Wendy M. Blumenschein, Dan G. Duda, Alona Muzikansky, Rakesh K. Jain, Patrick Y. Wen and David A. Reardon
Lakshmi Nayak
1Dana-Farber Cancer Institute, Boston, Massachusetts.
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Annette M. Molinaro
2University of California San Francisco, San Francisco, California.
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Katherine Peters
3Duke University Medical Center, Durham, North Carolina.
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Jennifer L. Clarke
2University of California San Francisco, San Francisco, California.
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  • ORCID record for Jennifer L. Clarke
Justin T. Jordan
4Massachusetts General Hospital, Boston, Massachusetts.
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John de Groot
5M.D. Anderson Cancer Center, Houston, Texas.
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Leia Nghiemphu
6University of California, Los Angeles, Los Angeles, California.
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Thomas Kaley
7Memorial Sloan Kettering Cancer Center, New York City, New York.
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Howard Colman
8Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
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Christine McCluskey
1Dana-Farber Cancer Institute, Boston, Massachusetts.
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Sarah Gaffey
1Dana-Farber Cancer Institute, Boston, Massachusetts.
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Timothy R. Smith
9Brigham and Women's Hospital, Boston, Massachusetts.
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David J. Cote
9Brigham and Women's Hospital, Boston, Massachusetts.
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Mariano Severgnini
1Dana-Farber Cancer Institute, Boston, Massachusetts.
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Jennifer H. Yearley
10Merck & Co., Inc., Kenilworth, New Jersey.
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Qing Zhao
10Merck & Co., Inc., Kenilworth, New Jersey.
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Wendy M. Blumenschein
10Merck & Co., Inc., Kenilworth, New Jersey.
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Dan G. Duda
4Massachusetts General Hospital, Boston, Massachusetts.
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Alona Muzikansky
4Massachusetts General Hospital, Boston, Massachusetts.
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Rakesh K. Jain
4Massachusetts General Hospital, Boston, Massachusetts.
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Patrick Y. Wen
1Dana-Farber Cancer Institute, Boston, Massachusetts.
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David A. Reardon
1Dana-Farber Cancer Institute, Boston, Massachusetts.
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  • For correspondence: david_reardon@dfci.harvard.edu
DOI: 10.1158/1078-0432.CCR-20-2500
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This OnlineFirst version was published on December 30, 2020
doi: 10.1158/1078-0432.CCR-20-2500

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Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma
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Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma
Lakshmi Nayak, Annette M. Molinaro, Katherine Peters, Jennifer L. Clarke, Justin T. Jordan, John de Groot, Leia Nghiemphu, Thomas Kaley, Howard Colman, Christine McCluskey, Sarah Gaffey, Timothy R. Smith, David J. Cote, Mariano Severgnini, Jennifer H. Yearley, Qing Zhao, Wendy M. Blumenschein, Dan G. Duda, Alona Muzikansky, Rakesh K. Jain, Patrick Y. Wen and David A. Reardon
Clin Cancer Res December 30 2020 DOI: 10.1158/1078-0432.CCR-20-2500

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Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma
Lakshmi Nayak, Annette M. Molinaro, Katherine Peters, Jennifer L. Clarke, Justin T. Jordan, John de Groot, Leia Nghiemphu, Thomas Kaley, Howard Colman, Christine McCluskey, Sarah Gaffey, Timothy R. Smith, David J. Cote, Mariano Severgnini, Jennifer H. Yearley, Qing Zhao, Wendy M. Blumenschein, Dan G. Duda, Alona Muzikansky, Rakesh K. Jain, Patrick Y. Wen and David A. Reardon
Clin Cancer Res December 30 2020 DOI: 10.1158/1078-0432.CCR-20-2500
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Clinical Cancer Research
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