PT - JOURNAL ARTICLE AU - Mandelker, Diana TI - Toward Concurrent Testing for Somatic and Germline Variants in Cancer Patients AID - 10.1158/1078-0432.CCR-16-1043 DP - 2016 Aug 15 TA - Clinical Cancer Research PG - 3987--3988 VI - 22 IP - 16 4099 - http://clincancerres.aacrjournals.org/content/22/16/3987.short 4100 - http://clincancerres.aacrjournals.org/content/22/16/3987.full SO - Clin Cancer Res2016 Aug 15; 22 AB - Sequencing for somatic alterations in patients' tumors is being increasingly clinically implemented to detect mutations that may guide therapy. Germline analysis of a cohort of patients undergoing tumor sequencing with matched normal has revealed that a small but significant percentage of these patients have germline variants that confer cancer susceptibility. Clin Cancer Res; 22(16); 3987–8. ©2016 AACR.See related article by Seifert et al., p. 4087