Table 2

List of the significantly altered expressed genes in prostate tumors compared with normal prostate specimens

GenesNormal prostate specimens (n = 7)aProstate tumors (n = 14)RatioROC-AUC
XDLD1 (LYVE1)b0.93c0.11d0.1160.000
ILK 0.970.460.4740.009
DCC 0.970.120.1220.013
NRG1 0.870.060.0720.017
BMP7 1.020.350.3440.024
NOS1 10.090.0950.025
SRD5A2 1.120.160.1440.032
SERPINB5 (Maspin)1.040.110.1030.037
FGR2IIIB 0.880.250.2820.037
ITG3B 0.990.390.3930.041
NTN1 (netrin-1)0.950.250.2670.045
GSTP1 (GSTπ)1.040.350.3360.049
ITGA5 0.830.240.2850.053
GRO1 1.010.220.2180.055
AREG 1.150.160.1350.063
PROK1 10.120.1240.067
SPARC-LIKE 0.980.60.6110.070
IGB4 0.990.290.2960.072
CALD1 10.390.3950.072
PIA2 0.790.170.210.075
THBD (thrombomodulin)0.910.280.3090.077
ROBO 1 0.870.340.3910.078
GJA1 (connexin 43)1.020.490.480.100
MMP14 0.940.510.540.105
CD44 1.020.450.4410.117
NOS2A 0.910.230.2590.124
SIAT 0.930.380.410.130
SFN (Stratifin)1.250.220.1770.133
TYMS 0.860.550.6320.148
CD13 0.650.060.0870.149
CXR4 0.960.460.4790.157
CYP1B1 0.970.490.5050.158
GRP 0.960.170.1770.165
CAV1 1.010.280.2810.193
CHGA 0.780.120.1540.200
RET 1.180.230.1980.208
ROBO 2 0.870.470.5400.212
UNC5C 0.840.530.6310.221
CDKN2B (p15)0.940.490.5210.222
SLIT 3 0.840.480.5710.255
EDNRB (ETB)0.780.480.6150.273
COL1A1 0.941.892.0040.761
MMP9 1.081.961.8120.785
PCA3 (DD3)0.992.182.2020.829
GRPR 13.143.1430.885
CDKN2A (p16)0.895.095.6860.969
  • a Mann-Whitney U test.

  • b Locus Link (Usual name).

  • c,d Numbers represent Ntarget (see “Materials and Methods”) medians of normal prostate specimens and prostate tumors, respectively.