Table 4

Most frequent drug-related adverse events IDEAL-1a

Adverse eventIDEAL-1IDEAL-2
250 mg/day (n = 103)500 mg/day (n = 105)250 mg/day (n = 102)500 mg/day (n = 114)
Rash, %
 Any grade47694351
 Grade 3 or 41703
Diarrhea, %
 Any grade40585375
 Grade 3 or 40716
Pruritus, %
 Any grade303688
 Grade 3 or 40101
Dry skin, %
 Any grade27291327
 Grade 3 or 40000
Nausea, %
 Any Grade12241318
 Grade 3 or 41111
  • a See Ref. 3 .