Table 2

Nonhematological toxicities

Cycle no.No. of patients/ cyclesNo. of patients with toxicitya
CardiologyDermatologyGastrointestinalNeurological
EdemaFlushingPruritusDiarrheaNausea/ vomitingAbdominal painPerioral numbnessPeripheral neuropathy
Grade 1Grade 2–3Grade 1Grade 2–3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1Grade 2–3
Cycle 116/160020000090108020
Cycle 214/140000201010122000
Cycle ≥36/131000000020200000
  • a Common Toxicity Criteria, version 2.