Multivariate analysis of clinicopathological parameters and nuclear Stat3 expression
Multivariate analysis of Stat3 and prognostic factors with 5 year overall survival with 198 tumors (performed using a Cox proportional hazards model).
| Variable | OSaP | Hazard ratio (95% CI) |
|---|---|---|
| Nuclear grade (high) | 0.1958 | 2.25 (0.66–7.72) |
| Ki-67 (high) | 0.4821 | 1.33 (0.60–2.93) |
| ER (neg) | 0.9330 | 1.04 (0.44–2.45) |
| PR (neg) | 0.4910 | 1.29 (0.62–2.70) |
| Her2 (pos) | 0.9973 | 0.99 (0.38–2.55) |
| Age (young) | 0.7682 | 0.81 (0.41–1.93) |
| Tumor size (>2 cm) | 0.0341 | 2.29 (1.06–4.93) |
| Stat3 nuclear staining (neg) | 0.0556 | 2.85 (0.97–8.33) |
a OS, overall survival; CI, confidence interval; neg, negative; pos, positive.