Table 2

Multivariate analysis of clinicopathological parameters and nuclear Phospho-Stat3 (Tyr705) expression

Multivariate analysis of Phospho-Stat3 (Tyr705) and prognostic factors with 5-year overall survival with 195 tumors (performed using a Cox proportional hazards model).

VariableOS PHazard ratio (95% CI)
Nuclear grade (high)0.06743.96 (0.91–16.82)
Ki-67 (high)0.54001.28 (0.56–2.78)
ER (neg)0.69350.84 (0.35–2.03)
PR (neg)0.79721.10 (0.53–2.30)
Her2 (pos)0.83101.11 (0.43–2.84)
Age (young)0.37641.42 (0.65–3.10)
Tumor size (>2 cm) 0.0412 2.21 (1.03–4.74)
Phospho-Stat3 (Tyr705) nuclear staining (neg) 0.0469 2.35 (1.01–5.46)
  • OS, overall survival; CI, confidence interval; neg, negative; pos, positive.