Table 2

Cell growth IC50 for PD166326 (all values in nm)

Cell typeBcr-ablPD166326 IC50
K562+0.3
BaF3 p210Bcr-abl+6.0
MCF-7 (breast cancer)1000.0
MDA-MB-468 (breast cancer)2000.0
32D (immortalized myeloid)800.0
BaF3 (immortalized myeloid)1000.0