Genotype | Cases n (%) | Controls n (%) | OR^{a} (95% CI) | OR^{b} (95% CI) |
---|---|---|---|---|
N/H372^{c} | ||||
All | ||||
A1/A1 | 97 (65) | 95 (62) | 1.0 | 1.0 |
A1/A2 | 47 (32) | 56 (36) | 0.82 (0.51–1.33) | 0.79 (0.48–1.30) |
A2/A2 | 5 (3) | 3 (2) | 1.60 (0.37–6.91) | 1.65 (0.36–7.58) |
Premenopausals | ||||
A1/A1 | 50 (67) | 38 (61) | 1.0 | 1.0 |
A1/A2 | 24 (32) | 21 (34) | 0.89 (0.43–1.84) | 0.74 (0.33–1.65) |
A2/A2 | 1 (1) | 3 (5) | 0.25 (0.02–2.46) | 0.22 (0.02–2.32) |
Postmenopausals | ||||
A1/A1 | 47 (64) | 57 (62) | 1.0 | 1.0 |
A1/A2 | 23 (31) | 35 (38) | 0.80 (0.41–1.56) | 0.64 (0.30–1.34) |
A2/A2 | 4 (5) | 0 (0) | ||
M/V784^{d} | ||||
All | ||||
A1/A1 | 118 (79) | 134 (87) | 1.0 | 1.0 |
A1/A2 | 31 (21) | 20 (13) | 1.78 (0.96–3.29) | 2.03 (1.07–3.87) |
A2/A2 | 0 (0) | 0 (0) | ||
Premenopausals | ||||
A1/A1 | 57 (76) | 54 (87) | 1.0 | 1.0 |
A1/A2 | 18 (24) | 8 (13) | 2.12 (0.85–5.28) | 2.22 (0.82–5.96) |
A2/A2 | 0 (0) | 0 (0) | ||
Postmenopausals | ||||
A1/A1 | 61 (82) | 80 (87) | 1.0 | 1.0 |
A1/A2 | 13 (18) | 12 (13) | 1.54 (0.64–3.71) | 1.90 (0.75–4.83) |
A2/A2 | 0 (0) | 0 (0) |
^{a} Adjusted for age.
^{b} Adjusted for age, first-degree family history of breast cancer, age at first live birth, and body mass index.
^{c} N/H372: A1 allele (N372); A2 allele (H372).
^{d} M/V784: A1 allele (M784); A2 allele (V784).