Table 1

Significant associations between serum level of CYFRA 21-1 and stage, surgical resection, and survival of lung cancera

AuthorYearNo.StageSurgerySurvival
Pujol’93165YesYes
Stieber’93200Yes
Ebert’94177NoYes
van der Gaast’94212Yes
Niklinski’94115YesNo
Bombardieri’94496Yes
Molina’94136Yes
Takada’95149Yes
Wieskopf’95116YesYes
Moro’95105YesYes
Niklinski’9557YesYes
Niklinski’9576YesYes
Muraki’96114Yes
Lai’96139Yes
Ebert’96108Yes
Pujol’96314YesYes
Niklinski’9691YesYes
Szturmowicz’9678NoNo
Brechot’97116YesYes
Ebert’97129Yes
Takei’9770YesYes
Huang’9787YesYes
Nisman’9894YesYes
  • a Significant increases in stage with increasing levels of CYFRA 21-1 are denoted under the stage column by a “Yes.” Significant drops in CYFRA 21-1 after surgical resection are denoted under the surgery column by a “Yes.” Significant decreases in survival with higher levels of pretreatment CYFRA 21-1 are denoted under the survival column by a “Yes.”