Table 2

Ki-67 LI, MVD, and AI of tumor cells in locally confined RCC

To examine the proliferation or apoptosis of tumor cells, sections of tumor tissues were stained with anti-Ki-67 antibody or by the TUNEL method. Ki-67 LI and AI were expressed as positively stained nuclei/total nuclei × 100 (%). For examination of MVD, sections were stained with anti-CD31 antibody to visualize endothelial cells, and MVD was expressed as the number of CD31-positive microvessels/mm2 in tumor tissues. Data represent the mean values ± 95% confidence interval.

TSP1 expressionP4N1K immunoreactivityP
Negative (n = 48)Positive (n = 34)Negative (n = 50)Positive (n = 32)
Ki-67 LI (%)5.3 ± 4.94.7 ± 3.80.2495.2 ± 4.74.8 ± 4.10.707
MVD (mm2)130 ± 55121 ± 440.436141 ± 51104 ± 41<0.001
AI (%)1.76 ± 0.791.85 ± 2.030.7701.51 ± 0.622.24 ± 2.100.023