Table 3

Occurrence of CIS or invasive cancer in patients with: MD (A), MD (B), and SD (C) at baseline biopsy

PatientA. MD
DaNo. of molecular abnormalitiesCarcinomabCISbTotal
110000
213000
310000
411101
5c21011
610000
712000
8c10101
9c12011
10c13011
11c12101
PatientB. MD
DNo. of molecular abnormalitiesCarcinomaCISTotal
113000
211000
3c20 and 3011
413101
522 and 2000
611101
7c13011
PatientC. SD
DNo. of molecular abnormalitiesCarcinomaCISTotal
113101
213000
314011
411000
513011
613000
712112
813011
913011
  • a Number of dysplastic area.

  • b Carcinoma and CIS are diagnosed additionally after baseline biopsy.

  • c Patients with another high-grade lesion.