Table 2

Associations between CIMP+ and clinicopathological or molecular features

Feature (n)CIMP− (%)CIMP+ (%)P
Total (206)139 (67)67 (33)
Sex
 Female (74)50 (68)24 (32)
 Male (132)89 (67)43 (33)0.98
Agea
 <62 yrs (105)70 (67)35 (33)
 ≥62 yrs (101)69 (68)32 (32)0.80
Site
 Rectum (49)42 (86)7 (14)
 Distal colon (47)40 (85)7 (15)
 Proximal (110)57 (52)53 (48)<0.005
Grade
 Well/moderate (162)116 (72)46 (28)
 Poor (41)20 (49)21 (51)<0.005
Nodal involvement
 1 or 2 nodes (89)59 (66)30 (34)
 ≥3 nodes (94)63 (67)31 (33)0.9
p53
 Wild-type (110)65 (59)45 (41)
 Mutant (76)61 (80)15 (20)<0.005
MSI
 Negative (165)120 (73)45 (27)
 Positive (28)8 (29)20 (71)<0.005
  • a Median age of patients was 62 years.