Table 1

β-Catenin mutations in colorectal carcinomas and colorectal cancer cell lines

SampleLocationβ-Catenin mutationMSIAPC mutation
NameTypeCodonMutation
207TumorAscendinga32GAC→AAC+bc
395TumorAscending45TCT→TTT+
396TumorAscending45In-frame deletion+
400TumorAscending45TCT→TTT+
435TumorAscending41ACC→GCC+
SNU-407dCell lineTransversee41ACC→GCC+
SNU-1047dCell lineTransverse45TCT→TTT+4107delC
LS174TfCell lineColong45TCT→TTT+
HCT 116fCell lineColong45In-frame deletion+
  • a Ascending colon.

  • b MSI in BAT-26.

  • c No APC mutation was found in MCR.

  • d These two cell lines were reported in our previous work (26) .

  • e Transverse colon.

  • f These cell lines were reported previously (21) .

  • g Detailed information on the origin of these cell lines could not be found. It was confirmed that these cell lines originated from human colon adenocarcinomas.