Mean | Range | |
---|---|---|
Tumor variables | ||
MMP-9 (% of points) | 11.4 | 0.2–29.2 |
p53 (% of points) | 14.6 | 0.0–67.0 |
Ki-67 (% of points) | 4.0 | 0.0–18.2 |
Nuclear volume (μm^{3}) | 12.1 | 0.3–45 |
AgNOR (μm^{2}) | 9.0 | 3.2–19.6 |
Stromal variables | ||
Vessels (no. per area) | 7.3 | 0.2–29.1 |
Stroma (% of points) | 21.0 | 0.0–85.9 |
Elastin [log(area)] | 9.0 | 5.6–11.0 |
Collagen [log(area)] | 9.4 | 7.5–11.2 |
^{a} The units of “% of points” indicate the number of points overlying the phenomena of interest divided by the total number of points overlying tumor. In morphometry, this is called a point fraction and is often symbolized as Pp. Pp has been shown to approximate the volume fraction or Vv (29) . The units for elastin and collagen are log(area) with the area determined by optical density (see “Patients and Methods”).