Table 2.

Effect of therapeutic agents on metastases in the MDA-MB-231-mCherry orthotopic model

VehicleDoxMapaLexa
Lymph node metastases per mousea9.2 ± 0.75.9 ± 0.8b7.0 ± 1.03.7 ± 0.9c
Mice with lung metastases, n10/11 (91)5/11 (45)5/11 (45)1/10 (10)

NOTE: Values in parentheses are given in percentage.

  • aData are the mean ± SEM.

  • bP < 0.05.

  • cP < 0.001 versus vehicle control.