Table 3.

Number (%) of patients with more than 5% grade 3/4 adverse events in either arm

Docetaxel/prednisone/custirsenMitoxantrone/prednisone/custirsen
N = 20N = 22
Lymphopenia6 (30%)7 (32%)
Fatigue7 (35%)5 (23%)
Asthenia3 (15%)4 (18%)
Neutropenia2 (10%)4 (18%)
Leukopenia1 (5%)4 (18%)
Dyspnoea1 (5%)4 (18%)
Anemia3 (14%)
Bone pain1 (5%)3 (14%)
Hyponatremia3 (14%)
Insomnia3 (14%)
Syncope2 (10%)
Chest pain2 (9%)
Headache2 (9%)
Infections2a (9%)1b (5%)
Febrile neutropenia2 (9%)
Nausea2 (9%)
  • aUrinary tract infection and injection site infection.

  • bPneumonia and septicemia.