Patient characteristics
| Characteristics | No. | % |
|---|---|---|
| Age, y | ||
| Median | 56.5 | |
| Range | 45–77 | |
| Initial tumor | ||
| Oropharynx | 8 | 44.4 |
| Larynx | 6 | 33.3 |
| Hypopharynx | 1 | 5.6 |
| Oral cavity | 2 | 11.1 |
| Multi | 1 | 5.6 |
| ECOG performance status | ||
| 0 | 3 | 16.7 |
| 1 | 12 | 66.7 |
| 2 | 3 | 16.7 |
| No. of cycles received | ||
| 1 | 2 | 11.1 |
| 2 | 8 | 44.4 |
| 3 | 0 | 0.0 |
| 4 | 4 | 22.2 |
| 5 | 0 | 0.0 |
| 6 | 2 | 11.1 |
| 7 | 0 | 0.0 |
| 8 | 1 | 5.6 |
| 9+ | 1 | 5.6 |
| Overall response rate (n = 17) | ||
| CR + PR | 4 | 26a |
| SD | 8 | 47 |
| PD | 5 | 29 |
aEstimated response rate is adjusted for Simon 2-stage design which proceeds to stage II if there is sufficient activity in stage I. Sample size is 18 for all variables, except response rate because of inevaluability of 1 patient.