Table 2.

Toxicities

Adverse eventGrade 3%Grade 4%
Constitutional
 Fatigue15.600.0
Hematologic
 Neutropenia422.2527.8
 Leukopenia316.7316.7
 Anemia15.600
 Thrombocytopenia15.6211.1
Nonhematologic
 Cough15.600
 Hypocalcemia15.600
 Hypophosphatemia15.600
 Hyponatremia211.100
 Hypokalemia15.600
 Nausea15.600
 Vomiting15.600
 Infection211.100
 DVT15.600
 Dysphagia15.600

NOTE. Of note, 8/18 patients (44.4%) did not experience significant (>grade 2) toxicity. Patients were assessed on day 1 of every 21-day cycle for changes in performance status and the presence of toxicities. Toxicities were graded according to CTCAE Version 3.0.