Table 1.

Summary of some of the ongoing clinical trials in which small-molecule inhibitors of p38 are being used

ConditionDrugPhase
Multiple myelomaSCIO-469Phase IIa
Bone marrow diseases, myelodysplastic syndromes, hematologic diseasesSCIO-469Phase Ia Phase IIa
Rheumatoid arthritisRO4402257Phase IIa
PH-797804Phase IIa
Neuropathic painSB681323Phase IIa
Acute lung injury, acute respiratory distress syndromeSB681323Phase IIb
AtherosclerosisBMS-582949Phase IIa

More information on these and other trials can be found at http://www.clinicaltrials.gov.

  • aThis study has been completed.

  • bThis study is currently recruiting participants.