Table 5.

Association of CYP2D6 genotype with odds of breast cancer risk

TreatmentStatusEM/EM (baseline)EM/IMIM/IMEM/PMPM/IMPM/PMMissing genotype data
TamoxifenControls24386819529322
Cases1294649723163
OR10.9941.0960.9471.4610.895
95% CI(0.651–1.518)(0.309–3.889)(0.677–1.325)(0.787–2.711)(0.462–1.736)
P0.9790.8880.750.2290.743
RaloxifeneControls22661417534283
Cases1074747222210
OR11.6712.4170.871.3211.597
95% CI(1.052–2.653)(0.513–11.379)(0.605–1.25)(0.747–2.335)(0.872–2.924)
P0.030.2640.4510.3380.129
TotalControls4691471237063605
Cases23693816945373
OR11.2571.5660.9161.3861.213
95% CI(0.922–1.713)(0.601–4.085)(0.717–1.171)(0.914–2.103)(0.778–1.891)