Table 1.

Characteristics of breast cancer cell lines and radiation sensitization

Cell lineCharacteristicsTGFβ-mediated growth inhibition at 48 hDose enhancement ratio at 10% survival
SubtypeERaP53b
MCF10ABasal BNegWT35%1.18
Hs578TBasal BNegMT22%1.04c
MDA-MB-231Basal BNegMTNone1.26
MCF7LuminalPosWTNone1.7
T47DLuminalPosWTNone1.26
  • aER: Estrogen receptor status.

  • bWT: Wild type; MT: Mutant.

  • cDER was estimated based on extrapolation to 10% survival.