Table 1.

Patient baseline characteristics

Baseline characteristicsNo. patients/median (range)
BreastOvarian
No. of patients1214
Measurable disease1213
Age, y60 (32–75)55 (39–73)
Performance status
 ECOG 025
 ECOG 1109
 ER+/PR+6N/A
Her2/neu+2N/A
Prior therapy
 Prior chemoregimens3 (0–8)5 (1–9)
 <3 chemoregimens32
 ≥3 chemoregimens912
 Radiation80
Concurrent trastuzumab2N/A
Time since last chemo, mo3 (1–19)1.5 (1–13)
CEA level3.5 ng/mL (0.7–153.6)N/A
CA 27.29 level167 U/mL (<12–276)N/A
CA-125 levelN/A135 U/mL (11–17,333)

Abbreviations: ECOG, Eastern Cooperative Oncology Group; N/A, not applicable.