AEs occurring in 10% or more of patients, regardless of the study drug relationship
| AEs, n (%) | Total (N = 47) | ||
|---|---|---|---|
| All grades | Grade 3 | Grade 4 | |
| Any | 47 (100) | 29 (61.7) | 6 (12.8) |
| Diarrhea | 36 (76.6) | 5 (10.6) | 0 |
| Fatigue | 36 (76.6) | 12 (25.5) | 1 (2.1) |
| Nausea | 36 (76.6) | 4 (8.5) | 0 |
| Vomiting | 22 (46.8) | 2 (4.3) | 0 |
| Weight decrease | 17 (36.2) | 0 | 0 |
| Anorexia | 16 (34.0) | 2 (4.3) | 0 |
| Abdominal pain, upper | 12 (25.5) | 4 (8.5) | 0 |
| Dysgeusia | 12 (25.5) | 0 | 0 |
| Rash | 12 (25.5) | 1 (2.1) | 0 |
| Dyspnea | 11 (23.4) | 0 | 0 |
| Dehydration | 10 (21.3) | 4 (8.5) | 0 |
| Back pain | 9 (19.1) | 2 (4.3) | 0 |
| Dizziness | 9 (19.1) | 0 | 0 |
| Dry mouth | 8 (17.0) | 0 | 0 |
| Urinary tract infection | 8 (17.0) | 0 | 0 |
| Constipation | 7 (14.9) | 0 | 0 |
| Dyspepsia | 7 (14.9) | 0 | 0 |
| Pyrexia | 7 (14.9) | 0 | 0 |
| Cough | 6 (12.8) | 1 (2.1) | 0 |
| Headache | 6 (12.8) | 0 | 0 |
| Abdominal pain | 5 (10.6) | 0 | 0 |
| Hypertriglyceridemia | 5 (10.6) | 3 (6.4) | 1 (2.1) |
| Myalgia | 5 (10.6) | 0 | 0 |
| Tachycardia | 5 (10.6) | 0 | 0 |