Table 2.

Scientific productivity for phase III trials, excluding trials closed less than 7 years without a principal publication to date (n = 20)

Phase III trials, n (%)
AllTherapeuticNontherapeutic
N = 218n = 167n = 51
Resulted in principal publication172 (79)135 (81)37 (73)
Answered intended scientific question159 (73)125 (75)34 (67)
 Positive results62 (39)52 (42)10 (29)
 Negative results97 (61)73 (58)24 (71)
Inconclusive13 (6)10 (6)3 (6)
Closed ≥ 7 years without a principal publication46 (21)32 (19)14 (27)