Table 1.

Results of real-time quantitative RT-PCR of IL-22, CCL20, and CCR6 and immunohistochemical analysis of IL-22, CCL20, CCR6, and phosphorylated STAT3 in 12 CTCL patients

AgeSexStageReal-time RT-PCRImmunohistochemistry
IL-22CCL20CCR6IL-22CCL20CCR6pSTAT3
54MalePatch MF1.74 × 10–25.01 × 10–37.72 × 10–4++
63MalePlaque MFNDND3.62 × 10–4±
52FemalePlaque MFNDND2.26 × 10–4+±+
64MalePlaque MFND8.37 × 10–33.62 × 10–4+±+++
33MalePlaque MF1.81 × 10–27.35 × 10–42.77 × 10–4+++
50FemalePlaque MF1.91 × 10–21.27 × 10–35.23 × 10–4+++++
56MaleTumor MF1.54 × 10–24.13 × 10–39.70 × 10–4++±±++
66FemaleTumor MF2.80 × 10–22.01 × 10–26.27 × 10–4+++++
60FemaleTumor MF1.37 × 10–12.72 × 10–31.17 × 10–2+++++++
41MaleErythrodermic MF1.13 × 10–11.95 × 10–24.51 × 10–2+++++++++
58FemaleSS1.20 × 10–17.15 × 10–32.69 × 10–3+++±±++
65FemaleSS1.99 × 10–13.02 × 10–21.05 × 10–1+++++++++++

ND, not detected.