Table 4.

Hematologic toxicity by maximum toxicity grade among patients whose toxicity worsened relative to baseline, across all cohorts and all cycles

Schedule 3/1 (n = 41)
Hematologic abnormalities, n (%)aGrade 1/2Grade 3/4
Hemoglobinb22 (55)3 (8)
Lymphocytesc14 (36)14 (36)
Neutrophilsc21 (54)8 (21)
Plateletsb18 (45)0
Leukocytesb27 (68)9 (23)
  • aLaboratory results by maximum toxicity grade among patients whose toxicity worsened relative to baseline.

  • bForty of 41 patients.

  • c39 of 41 patients in the schedule 3/1 group with baseline value and at least one post-baseline value patients assessable.