Table 1.

Patient demographics

Patient characteristicsNumber of patients (phase I)Number of patients (phase II)Total number of patients
Total number131831
Median age (range), y55.5 (27–79)60.5 (48–74)60 (27–79)
Male/female7/617/124/7
Performance status
 0235
 1/2111526
Race
 White101525
 Asian325
 Other011
Tumor type
 SCCHN21214
 HNC (other histologiesa)4610
 Melanoma303
 Gynecologic cancer202
 Sarcoma101
 Unknown primary101
Months elapsed since diagnosis (median, range)39.1 (1.5–137.5)35.5 (8.6–127.6)37.0 (1.5–137.5)
  • aOther HNC histologies include nasopharyngeal cancer, adenoid cystic carcinoma, squamous cell carcinoma of the skin, and sinonasal undifferentiated carcinoma.