Table 4.

Comparison of competing risks regression models examining treatment and two covariates for competing outcomes in prostate cancer (RTOG 8610)

Model effect estimates
Cox CSHFine–Gray SDHKlein—Andersen
Event type (death)CHR (95% CI)SHR (95% CI)SHR (95% CI)
Outcome 1: Prostate cancer
 ADT (vs. RT only)0.67 (0.49–0.92)0.66 (0.48–0.91)0.67 (0.49–0.93)
 Agea0.89 (0.71–1.13)0.75 (0.60–0.95)0.79 (0.63–1.00)
 Grade 2 vs. 11.84 (1.04–3.23)1.83 (1.05–3.17)1.87 (1.06–3.31)
 Grade 3 vs. 12.87 (1.66–4.98)2.83 (1.65–4.87)2.94 (1.70–5.08)
Outcome 2: Other causes
 ADT (vs. RT only)1.13 (0.85–1.51)1.26 (0.95–1.68)1.20 (0.89–1.61)
 Agea2.02 (1.60–2.57)1.93 (1.54–2.43)1.88 (1.49–2.38)
 Grade 2 vs. 10.87 (0.59–1.28)0.75 (0.52–1.08)0.82 (0.56–1.20)
 Grade 3 vs. 10.91 (0.62–1.35)0.60 (0.41–0.87)0.61 (0.41–0.90)
All deaths
 ADT (vs. RT only)0.88 (0.71–1.09)
 Age1.36 (1.15–1.61)
 Grade 2 vs. 11.13 (0.83–1.55)
 Grade 3 vs. 11.44 (1.06–1.97)
  • aPer 10 y increment in age.