Characteristic | Points with CTC data | P value Mann–Whitney |
---|---|---|

Age, y | ||

<65 | 24 | |

≥65 | 13 | |

P | 0.0556 | |

Race | ||

Caucasian | 33 | |

Asian | 4 | |

P | 0.5572 | |

Histology | ||

Adenocarcinoma | 24 | |

Squamous | 9 | |

P | 0.9837 | |

Gender | ||

Male | 21 | |

Female | 16 | 0.8042 |

Smoking | ||

Yes | 31 | |

No | 6 | |

P | 0.8026 | |

Genotype | ||

EGFR mut | 8 | |

EGFR WT | 21 | |

KRAS mut | 7 | |

KRAS WT | 24 | |

EGFR WT, KRAS WT | 14 | |

P value EGFR mut vs. WT | 0.0941 | |

P value KRAS mut vs. WT | 0.1808 | |

P value EGFR mut vs. WT for KRAS and EGFR | 0.0621 | |

P value KRAS mut vs. WT for KRAS and EGFR | 0.0648 | |

Tumor burden | ||

Sld at baseline (below median) | 18 | |

Sld at baseline (above median) | 19 | |

P | 0.747 | |

RECIST response | ||

Partial response | 7 | |

Stable disease or progressive disease | 12 | |

P | 0.0091 | |

ECOG | ||

0 | 9 | |

1 | 21 | |

2 | 7 | |

P | 0.4813 | |

Blood shipment site | ||

Australia | 21 | |

US | 16 | |

P | 0.6309 | |

Blood shipment time | ||

≤3 d | 28 | |

>3 d | 6 | |

P | 0.3682 |

NOTE: *P* value is based on 2-tailed Mann–Whitney *U* test except for ECOG score which used a Kruskal–Wallis test for 3-way comparison.

Abbreviation: Sld, sum of the longest unidimensional diameter.