Table 4.

Duration of metformin use and OS

Metformin use, yNo. of patients (no. of deaths)Mean ± SE of survival timeHRa (95% CI)P
<247 (34)19.2 ± 1.91.0
2–522 (13)28.7 ± 4.90.54 (0.28–1.05)0.069
>520 (13)26.9 ± 5.50.82 (0.40–1.69)0.594
>2 (2–5 and >5)42 (26)27.6 ± 3.70.64 (0.37–1.10)0.109
  • aHR (95% CI) was adjusted for stage and serum level of CA-19-9.