Table 2.

Median survival in months (95% CI) for patients with different stages of disease by metformin use

All patients (N = 302)Metformin (N = 117)Non-metformin (N = 185)P
All patients12.8 (11.0–14.7)15.2 (12.6–17.8)11.1 (8.9–13.3)0.009
Stage
 Resectable28.2 (19.7–36.8)31.0 (15.2–46.8)21.4 (14.4–28.3)0.293
 Unresectable13.8 (11.2–16.5)15.5 (13.4–17.7)11.0 (8.7–13.3)0.001
 Metastatic8.3 (6.9–9.7)8.8 (7.0–10.6)7.3 (5.5–9.1)0.482
 Nonmetastatica16.6 (14.3–18.9)20.8 (15.7–26.0)14.8 (12.5–17.2)0.005
  • aCombined group of patients with resectable and unresectable disease.