Multivariate analysis of survival by independent predictors, including the RMH score variables (LDH, number of metastatic sites >2, and albumin) individually and then by including the RMH score by itself as a single variable
| Risk factors | RR for death (95% CI) | P |
|---|---|---|
| Albumin < 3.5 g/dLa | 1.66 (1.34–2.05) | <0.0001 |
| Number of metastatic sites > 2a | 1.34 (1.16–1.55) | 0.0001 |
| LDH > 618 IU/La,b | 1.78 (1.53–2.06) | <0.0001 |
| Gastrointestinal tumor type | 1.55 (1.34–1.80) | <0.0001 |
| ECOG PS ≥ 1 | 1.32 (1.13–1.55) | 0.0004 |
| Platelets > 440 K/UL | 1.35 (1.10–1.67) | 0.0047 |
| Number of prior therapies ≥ 3 | 1.33 (1.13–1.57) | 0.0007 |
| RMH score as single variable | ||
| RMH score > 1 | 1.97 (1.67–2.32) | <0.0001 |
| Gastrointestinal tumor type | 1.65 (1.43–1.92) | <0.0001 |
| ECOG PS ≥ 1 | 1.33 (1.13–1.55) | 0.0004 |
| Platelet > 440 K/UL | 1.43 (1.16–1.76) | 0.0008 |
| Number of prior therapies ≥ 3 | 1.43 (1.21–1.68) | <0.0001 |