Table 1.

Characteristics of 58 studies

PoorNeutralGood
FoxP3 prognosis claim232312
Specific antibody
 Clone 421
 Custom1
 BioLegend31
 Abcam641
 mAbcam22509211
 Novus Biologicals1
 FJK-16s1
 206D1
 eBioscience2
 236A/E71085
 mAbcam2251021
 PCH10121
 259D1
 eBio79791
 221D/D31
Scoring strategy
 Cutoff point
  Absence and/or presence133
  Mean cutoff131
  Median cutoff16115
  Other cutoff563
 Counting location
  General count555
  Tumor only874
  Tumor and stroma10113
 Tissue used
  Whole sections16177
  Tissue microarray765
 Counting strategy
  Investigator(s)16148
  Computer program42
  Not reported752
Multivariate correction for stage or grade
 Yes: 42201111
 No: 163121
Multivariate correction for other TIL subsets
 Yes: 8233
 No: 5021209
Use of multiple markers
 Yes: 844
 No: 50191912
Tumor site
 Hepatocellular5
 Cervical2
 Head and neck1
 Pancreatic1
 Renal11
 Lung11
 Endometrial12
 Melanoma22
 Breast512
 Mesothelioma1
 Vulvar1
 Oral131
 Gastric212
 Ovarian142
 Bladder1
 Colorectal64

NOTE: Study N mean (range): 219 (30–1,445).