Table 3.

p16/Ki-67 positivity in histology categories stratified by age and HPV16 status

NormalAtypical metaplasiaCIN1CIN2CIN3CancerTotal
Total11225228169836623
% DS+26.848.046.582.892.8100.059.6
HPV16− (<30)521413185180300
% DS+25.064.346.681.277.8N/A55.3
HPV16− (30+)4136422113144
% DS+24.4031.368.290.910040.3
HPV16+ (<30)1452552340130
% DS+28.640.072.092.397.1N/A80.8
HPV16+ (30+)416819347
% DS+50.0100.083.375.0100.0100.087.8

Abbreviations: DS+, p16/Ki-67 double-stain positive; N/A, not applicable.