Table 2.

Results of meta-regression analysis exploring source of heterogeneity with progression-free/disease-free and overall survival.

PFS/DFSOS
Univariate analysisUnivariate analysis
CovariatesCoefficientSEPCoefficientSEP
Detection method0.150.100.15−0.020.080.83
Time point of sampling−0.210.120.08−0.130.090.15
Stage of breast cancer−0.410.120.001−0.250.100.01
Sample size−0.0010.0010.250.00030.00060.64
Publication year−0.070.040.07−0.030.030.27

NOTE: The dependent variable is the lnHR for PFS/DFS or OS from each study. Weights have been assigned according to the estimated variance of the lnHR. SE, standard error of the coefficient.