Table 3.

Cox regression multivariate analysis of prognostic factors for OS in all patients

FactorGroupNumber of patients5-year survival (%)HR (95% CI)P value
ArmSurgery only41461.91
S-141573.60.617 (0.481–0.790)<0.001
SexMale56567.21
Female26469.00.988 (0.757–1.301)0.932
Age, y<6031869.51
60–6931072.21.242 (1.057–1.460)
70–8020158.41.544 (1.118–2.132)0.009
Cancer stage (Japanese classification)II37277.01
IIIa32163.71.683 (1.431–1.979)
IIIb13652.22.833 (2.048–3.918)<0.001
Histologic typeDifferentiated33265.11
Undifferentiateda49769.60.894 (0.684–1.171)0.412
EGFR statusNegative75469.01
Positive7555.41.504 (1.020–2.149)0.040
HER2 statusNegative71668.31
Positive11364.51.068 (0.736–1.514)0.722
  • aIncluding 3 patients with gastric cancer categorized into neither differentiated nor undifferentiated type.