Table 2.

Univariate analysis for overall survival

VariableNo. of patients5-y survival rateP value
Age, y
 <504947.40.20
 ≥503952.3
Sex
 Male4445.70.43
 Female4453.7
NF1
 Present3634.10.029
 Absent5258.8
Site
 Extremity3658.80.16
 Trunk5243.1
Tumor depth
 Superficial2079.40.0008
 Deep6840.5
Tumor size
 <5 cm2479.50.0012
 ≥5 cm6438.4
Adjuvant therapy
 Given425.00.024
 Not given8450.6
Tumor necrosis
 Absent3964.20.0096
 Present4937.9
Mitotic counts
 0–9/10 HPF5854.90.081
 ≥10/10 HPF3037.9
Ki-67 labeling index
 0%–29%6063.4<0.0001
 ≥30%2817.4
Rhabdomyoblastic differentiation
 Present1130.30.16
 Absent7752.0
Epithelioid feature
 Present616.70.040
 Absent8252.3
Histologic grade
 Low-grade2673.50.016
 High-grade6239.8
AJCC staging
 I2673.50.016
 II + III + IV6239.8
p-Akt
 Positive5142.00.045
 Negative3761.1
p-mTOR
 Positive4131.50.0039
 Negative4766.4
p-S6RP
 Positive4741.10.026
 Negative4158.8
p-p70S6K
 Positive4951.40.99
 Negative3946.2
p-4E-BP1
 Positive5551.60.68
 Negative3345.5
p-MEK1/2
 Positive8249.10.99
 Negative650.0
p-ERK1/2
 Positive7248.80.59
 Negative1651.1